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TRIM45 (tripartite motif containing 45)

Identity

Alias_namestripartite motif-containing 45
Alias_symbol (synonym)FLJ13181
RNF99
Other alias
HGNC (Hugo) TRIM45
LocusID (NCBI) 80263
Atlas_Id 49910
Location 1p13.1  [Link to chromosome band 1p13]
Location_base_pair Starts at 117111055 and ends at 117121789 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM45   19018
Cards
Entrez_Gene (NCBI)TRIM45  80263  tripartite motif containing 45
AliasesRNF99
GeneCards (Weizmann)TRIM45
Ensembl hg19 (Hinxton)ENSG00000134253 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134253 [Gene_View]  ENSG00000134253 [Sequence]  chr1:117111055-117121789 [Contig_View]  TRIM45 [Vega]
ICGC DataPortalENSG00000134253
TCGA cBioPortalTRIM45
AceView (NCBI)TRIM45
Genatlas (Paris)TRIM45
WikiGenes80263
SOURCE (Princeton)TRIM45
Genetics Home Reference (NIH)TRIM45
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM45  -     chr1:117111055-117121789 -  1p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM45  -     1p13.1   [Description]    (hg19-Feb_2009)
GoldenPathTRIM45 - 1p13.1 [CytoView hg19]  TRIM45 - 1p13.1 [CytoView hg38]
ImmunoBaseENSG00000134253
Mapping of homologs : NCBITRIM45 [Mapview hg19]  TRIM45 [Mapview hg38]
OMIM609318   
Gene and transcription
Genbank (Entrez)AK023243 AK222901 AY669488 BC034943 BU165629
RefSeq transcript (Entrez)NM_001145635 NM_025188
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIM45
Cluster EST : UnigeneHs.301526 [ NCBI ]
CGAP (NCI)Hs.301526
Alternative Splicing GalleryENSG00000134253
Gene ExpressionTRIM45 [ NCBI-GEO ]   TRIM45 [ EBI - ARRAY_EXPRESS ]   TRIM45 [ SEEK ]   TRIM45 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80263
GTEX Portal (Tissue expression)TRIM45
Human Protein AtlasENSG00000134253-TRIM45 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8W5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8W5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8W5
Splice isoforms : SwissVarQ9H8W5
PhosPhoSitePlusQ9H8W5
Domaine pattern : Prosite (Expaxy)FILAMIN_REPEAT (PS50194)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Bbox_C    Filamin/ABP280_repeat-like    Filamin/ABP280_rpt    Ig-like_fold    Ig_E-set    Znf-RING_LisH    Znf_B-box    Znf_RING    Znf_RING_CS   
Domain families : Pfam (Sanger)Filamin (PF00630)    zf-B_box (PF00643)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam00630    pfam00643    pfam13445   
Domain families : Smart (EMBL)BBC (SM00502)  BBOX (SM00336)  IG_FLMN (SM00557)  RING (SM00184)  
Conserved Domain (NCBI)TRIM45
DMDM Disease mutations80263
Blocks (Seattle)TRIM45
PDB (RSDB)2DS4   
PDB Europe2DS4   
PDB (PDBSum)2DS4   
PDB (IMB)2DS4   
Structural Biology KnowledgeBase2DS4   
SCOP (Structural Classification of Proteins)2DS4   
CATH (Classification of proteins structures)2DS4   
SuperfamilyQ9H8W5
Human Protein Atlas [tissue]ENSG00000134253-TRIM45 [tissue]
Peptide AtlasQ9H8W5
HPRD15562
IPIIPI00018747   IPI00477851   IPI00640286   IPI00982733   
Protein Interaction databases
DIP (DOE-UCLA)Q9H8W5
IntAct (EBI)Q9H8W5
FunCoupENSG00000134253
BioGRIDTRIM45
STRING (EMBL)TRIM45
ZODIACTRIM45
Ontologies - Pathways
QuickGOQ9H8W5
Ontology : AmiGOnucleoplasm  cytosol  zinc ion binding  intercellular bridge  bone development  
Ontology : EGO-EBInucleoplasm  cytosol  zinc ion binding  intercellular bridge  bone development  
NDEx NetworkTRIM45
Atlas of Cancer Signalling NetworkTRIM45
Wikipedia pathwaysTRIM45
Orthology - Evolution
OrthoDB80263
GeneTree (enSembl)ENSG00000134253
Phylogenetic Trees/Animal Genes : TreeFamTRIM45
HOGENOMQ9H8W5
Homologs : HomoloGeneTRIM45
Homology/Alignments : Family Browser (UCSC)TRIM45
Gene fusions - Rearrangements
Fusion : QuiverTRIM45
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM45
dbVarTRIM45
ClinVarTRIM45
1000_GenomesTRIM45 
Exome Variant ServerTRIM45
ExAC (Exome Aggregation Consortium)ENSG00000134253
GNOMAD BrowserENSG00000134253
Varsome BrowserTRIM45
Genetic variants : HAPMAP80263
Genomic Variants (DGV)TRIM45 [DGVbeta]
DECIPHERTRIM45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM45 
Mutations
ICGC Data PortalTRIM45 
TCGA Data PortalTRIM45 
Broad Tumor PortalTRIM45
OASIS PortalTRIM45 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM45  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM45
Mutations and Diseases : HGMDTRIM45
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM45
DgiDB (Drug Gene Interaction Database)TRIM45
DoCM (Curated mutations)TRIM45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM45 (select a term)
intoGenTRIM45
Cancer3DTRIM45(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609318   
Orphanet
DisGeNETTRIM45
MedgenTRIM45
Genetic Testing Registry TRIM45
NextProtQ9H8W5 [Medical]
TSGene80263
GENETestsTRIM45
Target ValidationTRIM45
Huge Navigator TRIM45 [HugePedia]
snp3D : Map Gene to Disease80263
BioCentury BCIQTRIM45
ClinGenTRIM45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80263
Chemical/Pharm GKB GenePA134873644
Clinical trialTRIM45
Miscellaneous
canSAR (ICR)TRIM45 (select the gene name)
DataMed IndexTRIM45
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM45
EVEXTRIM45
GoPubMedTRIM45
iHOPTRIM45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:13:07 CET 2019

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