TRIM58 (tripartite motif containing 58)

2003-12-01  

Identity

HGNC
TRIM58
LOCATION
1q44
LOCUSID
25893
ALIAS
BIA2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25893
HGNC: 24150
Ensembl: ENSG00000162722

Variants:

dbSNP: 25893
ClinVar: 25893
TCGA: ENSG00000162722
COSMIC: TRIM58

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162722ENST00000366481Q8NG06

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
279265162017Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.11
297495382018TRIM58/cg26157385 methylation is associated with eight prognostic genes in lung squamous cell carcinoma.11
299568132018Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.5
313837412019TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells.0

Citation

Dessen P

TRIM58 (tripartite motif containing 58)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/790/trim58