TRIM59 (tripartite motif containing 59)

2003-06-01  

Identity

HGNC
LOCATION
3q25.33
LOCUSID
ALIAS
IFT80L,MRF1,RNF104,TRIM57,TSBF1
FUSION GENES

Other Information

Locus ID:

NCBI: 286827
MIM: 616148
HGNC: 30834
Ensembl: ENSG00000213186

Variants:

dbSNP: 286827
ClinVar: 286827
TCGA: ENSG00000213186
COSMIC: TRIM59

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213186ENST00000309784Q8IWR1
ENSG00000213186ENST00000468542C9JNB9
ENSG00000213186ENST00000471155C9IZE0
ENSG00000213186ENST00000471396C9JE08
ENSG00000213186ENST00000479460C9J614
ENSG00000213186ENST00000494486C9J9F0
ENSG00000213186ENST00000496222C9IY67
ENSG00000213186ENST00000543469F5GZP3

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382912002024TRIM59 suppresses the brain ischaemia/reperfusion injury and pyroptosis of microglial through mediating the ubiquitination of NLRP3.0
389081952024Role of TRIM59 in regulating PPM1A in the pathogenesis of silicosis and the intervention effect of tanshinone IIA.0
382912002024TRIM59 suppresses the brain ischaemia/reperfusion injury and pyroptosis of microglial through mediating the ubiquitination of NLRP3.0
389081952024Role of TRIM59 in regulating PPM1A in the pathogenesis of silicosis and the intervention effect of tanshinone IIA.0
364171142023TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination.12
365440442023TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer.2
377400072023SLC35F2-SYVN1-TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53.4
379785152023A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification.0
364171142023TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination.12
365440442023TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer.2
377400072023SLC35F2-SYVN1-TRIM59 axis critically regulates ferroptosis of pancreatic cancer cells by inhibiting endogenous p53.4
379785152023A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification.0
346259082022TRIM59 promotes osteosarcoma progression via activation of STAT3.5
353779642022Evaluation of tripartite motif 59 and its diagnostic utility in benign bowel diseases and colorectal cancer.3
356036502022[Down-regulation of tripartite motif containing 59 (TRIM59) blocks the NF-κB signaling pathway and inhibits the invasion and migration of nasopharyngeal carcinoma cells].0

Citation

Dessen P

TRIM59 (tripartite motif containing 59)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42711/trim59