TRIM66 (tripartite motif containing 66)

2016-08-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
C11orf29,TIF1D,TIF1DELTA
FUSION GENES

Other Information

Locus ID:

NCBI: 9866
MIM: 612000
HGNC: 29005
Ensembl: ENSG00000166436

Variants:

dbSNP: 9866
ClinVar: 9866
TCGA: ENSG00000166436
COSMIC: TRIM66

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166436ENST00000299550O15016
ENSG00000166436ENST00000402157B5MCJ9
ENSG00000166436ENST00000530502H0YF52
ENSG00000166436ENST00000644261A0A2R8YE93
ENSG00000166436ENST00000646038A0A2R8YEA1

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
153221352004TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.28
262476332015TRIM66 overexpresssion contributes to osteosarcoma carcinogenesis and indicates poor survival outcome.22
299297492018Knockdown of TRIM66 inhibits malignant behavior and epithelial-mesenchymal transition in non-small cell lung cancer.5
289465632017TRIM66 expression in non-small cell lung cancer: A new predictor of prognosis.3
307105482019TRIM66 confers tumorigenicity of hepatocellular carcinoma cells by regulating GSK-3β-dependent Wnt/β-catenin signaling.1
314345452019miR-451a Inhibits the Growth and Invasion of Osteosarcoma via Targeting TRIM66.1
314721442019Knockdown of TRIM66 inhibits cell proliferation, migration and invasion in colorectal cancer through JAK2/STAT3 pathway.1
315377822019TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells.0

Citation

Dessen P

TRIM66 (tripartite motif containing 66)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55891/trim66