TROAP (trophinin associated protein)

2018-11-01  

Identity

HGNC
TROAP
LOCATION
12q13.12
LOCUSID
10024
ALIAS
TASTIN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10024
MIM: 603872
HGNC: 12327
Ensembl: ENSG00000135451

Variants:

dbSNP: 10024
ClinVar: 10024
TCGA: ENSG00000135451
COSMIC: TROAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135451ENST00000257909Q12815
ENSG00000135451ENST00000380327Q12815
ENSG00000135451ENST00000546735F8VR46
ENSG00000135451ENST00000546776F8VVT5
ENSG00000135451ENST00000547807F8W1E3
ENSG00000135451ENST00000547923F8W1U0
ENSG00000135451ENST00000548311Q12815
ENSG00000135451ENST00000549275F8VVX4
ENSG00000135451ENST00000549534F8VXV6
ENSG00000135451ENST00000549891F8VR46
ENSG00000135451ENST00000550346F8VVS4
ENSG00000135451ENST00000550709F8VXF3
ENSG00000135451ENST00000551192B7Z5Q9
ENSG00000135451ENST00000551245F8W130
ENSG00000135451ENST00000551567F8W052

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
302846522019High Trophinin-Associated Protein Expression Is an Independent Predictor of Poor Survival in Liver Cancer.23
120496302002Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton.12
182189222008Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis.10
291178812018Downregulated Trophinin-Associated Protein Plays a Critical Role in Human Hepatocellular Carcinoma Through Upregulation of Tumor Cell Growth and Migration.4
299568062018Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer.2
311987872019TROAP Promotes Breast Cancer Proliferation and Metastasis.0

Citation

Dessen P

TROAP (trophinin associated protein)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57747/troap