TSC22D1 (TSC22 domain family member 1)

2003-12-01 Affiliation

Identity

HGNC

TSC22D1

LOCATION

13q14.11

LOCUSID

8848

ALIAS

Ptg-2,TGFB1I4,TSC22

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8848
MIM: 607715
HGNC: 16826
Ensembl: ENSG00000102804

Variants:

dbSNP: 8848
ClinVar: 8848
TCGA: ENSG00000102804
COSMIC: TSC22D1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000102804	ENST00000261489	Q15714
ENSG00000102804	ENST00000261489	A0A024RDV8
ENSG00000102804	ENST00000458659	Q15714
ENSG00000102804	ENST00000472477	C9JYW3
ENSG00000102804	ENST00000486464	H7C4J9
ENSG00000102804	ENST00000493016	C9IZ15
ENSG00000102804	ENST00000501704	Q15714
ENSG00000102804	ENST00000611198	A0A087X0H8
ENSG00000102804	ENST00000622051	A0A087X0H8

Expression (GTEx)

100

150

200

250

300

350

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
12468551	2003	Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22.	19
15881652	2005	Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation.	18
16106424	2006	Differential expression of TGFbeta-stimulated clone 22 in normal prostate and prostate cancer.	13
20149264	2010	Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila.	11
17622752	2007	TGF-beta1 and TSC-22 gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes.	10
21448135	2011	Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.	9
22870275	2012	Crucial role of TSC-22 in preventing the proteasomal degradation of p53 in cervical cancer.	9
17690703	2007	Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD.	8
18325344	2008	Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22.	8
12767908	2003	Posttranscriptional regulation of TSC-22 (TGF-beta-stimulated clone-22) gene by TGF-beta 1.	6

Citation

Dessen P

TSC22D1 (TSC22 domain family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42536/tsc22d1