Identity
HGNC
LOCATION
2q14.3
LOCUSID
ALIAS
BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7247
MIM: 600575
HGNC: 12379
Ensembl: ENSG00000211460
Variants:
dbSNP: 7247
ClinVar: 7247
TCGA: ENSG00000211460
COSMIC: TSN
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Gene Silencing by RNA | REACTOME | R-HSA-211000 |
| Small interfering RNA (siRNA) biogenesis | REACTOME | R-HSA-426486 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36098897 | 2023 | Biochemical characterization of clinically relevant mutations of human Translin. | 0 |
| 36098897 | 2023 | Biochemical characterization of clinically relevant mutations of human Translin. | 0 |
| 33268667 | 2021 | Functional characterization of testis-brain RNA-binding protein, TB-RBP/Translin, in translational regulation. | 2 |
| 33268667 | 2021 | Functional characterization of testis-brain RNA-binding protein, TB-RBP/Translin, in translational regulation. | 2 |
| 31442605 | 2019 | Role of amino acid residues important for nucleic acid binding in human Translin. | 0 |
| 31442605 | 2019 | Role of amino acid residues important for nucleic acid binding in human Translin. | 0 |
| 28827400 | 2017 | UPF1 helicase promotes TSN-mediated miRNA decay. | 14 |
| 28827400 | 2017 | UPF1 helicase promotes TSN-mediated miRNA decay. | 14 |
| 27183912 | 2016 | Translin and Trax differentially regulate telomere-associated transcript homeostasis. | 5 |
| 27183912 | 2016 | Translin and Trax differentially regulate telomere-associated transcript homeostasis. | 5 |
| 25433126 | 2015 | A novel open-barrel structure of octameric translin reveals a potential RNA entryway. | 3 |
| 25433126 | 2015 | A novel open-barrel structure of octameric translin reveals a potential RNA entryway. | 3 |
| 24338081 | 2014 | Hydrolysis rates of different small interfering RNAs (siRNAs) by the RNA silencing promoter complex, C3PO, determines their regulation by phospholipase Cβ. | 9 |
| 25457613 | 2014 | Rescuing dicer defects via inhibition of an anti-dicing nuclease. | 25 |
| 24338081 | 2014 | Hydrolysis rates of different small interfering RNAs (siRNAs) by the RNA silencing promoter complex, C3PO, determines their regulation by phospholipase Cβ. | 9 |
Citation
Dessen P
TSN (translin)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42715/tsn
