TSNAX (translin associated factor X)

2003-06-01  

Identity

HGNC
LOCATION
1q42.2
LOCUSID
ALIAS
C3PO,TRAX
FUSION GENES

Other Information

Locus ID:

NCBI: 7257
MIM: 602964
HGNC: 12380
Ensembl: ENSG00000116918

Variants:

dbSNP: 7257
ClinVar: 7257
TCGA: ENSG00000116918
COSMIC: TSNAX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116918ENST00000366639Q99598
ENSG00000116918ENST00000366639A0A024R3V8
ENSG00000116918ENST00000413309Q5VVQ1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Gene Silencing by RNAREACTOMER-HSA-211000
Small interfering RNA (siRNA) biogenesisREACTOMER-HSA-426486

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
162758082005Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory.117
215522582011Structure of C3PO and mechanism of human RISC activation.63
176734522007Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.42
158385352005Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population.41
158385352005Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population.41
203989082010Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.32
147118182004Translin-associated factor X is post-transcriptionally regulated by its partner protein TB-RBP, and both are essential for normal cell proliferation.22
192555812010Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.22
192555812010Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.22
206914272010Genetic associations of brain structural networks in schizophrenia: a preliminary study.17

Citation

Dessen P

TSNAX (translin associated factor X)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42716/tsnax