Identity
HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
BPBS,BZRP,DBI,IBP,MBR,PBR,PBS,PKBS,PTBR,mDRC,pk18
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 706
MIM: 109610
HGNC: 1158
Ensembl: ENSG00000100300
Variants:
dbSNP: 706
ClinVar: 706
TCGA: ENSG00000100300
COSMIC: TSPO
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuroactive ligand-receptor interaction | KEGG | ko04080 |
| Neuroactive ligand-receptor interaction | KEGG | hsa04080 |
| HTLV-I infection | KEGG | ko05166 |
| HTLV-I infection | KEGG | hsa05166 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37801139 | 2024 | Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer's disease. | 3 |
| 37801139 | 2024 | Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer's disease. | 3 |
| 36973385 | 2023 | Investigating TSPO levels in occupation-related posttraumatic stress disorder. | 0 |
| 36980295 | 2023 | Impact of Translocator Protein 18 kDa (TSPO) Deficiency on Mitochondrial Function and the Inflammatory State of Human C20 Microglia Cells. | 1 |
| 37047353 | 2023 | Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97. | 3 |
| 37158962 | 2023 | TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma. | 1 |
| 37291448 | 2023 | [(18)F]DPA-714: Effect of co-medications, age, sex, BMI and TSPO polymorphism on the human plasma input function. | 2 |
| 37574731 | 2023 | TSPO Modulates Oligomeric Amyloid-β-Induced Monocyte Chemotaxis: Relevance for Neuroinflammation in Alzheimer's Disease. | 2 |
| 37580767 | 2023 | The mitochondrial protein TSPO in Alzheimer's disease: relation to the severity of AD pathology and the neuroinflammatory environment. | 4 |
| 37952221 | 2023 | Translocator protein (TSPO) expression in neoplastic cells and tumor-associated macrophages in meningiomas. | 0 |
| 36973385 | 2023 | Investigating TSPO levels in occupation-related posttraumatic stress disorder. | 0 |
| 36980295 | 2023 | Impact of Translocator Protein 18 kDa (TSPO) Deficiency on Mitochondrial Function and the Inflammatory State of Human C20 Microglia Cells. | 1 |
| 37047353 | 2023 | Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97. | 3 |
| 37158962 | 2023 | TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma. | 1 |
| 37291448 | 2023 | [(18)F]DPA-714: Effect of co-medications, age, sex, BMI and TSPO polymorphism on the human plasma input function. | 2 |
Citation
Dessen P
TSPO (translocator protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/858/tspo
