Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TSTA3 (tissue specific transplantation antigen P35B)

Identity

Alias_symbol (synonym)FX
P35B
SDR4E1
Other alias
HGNC (Hugo) TSTA3
LocusID (NCBI) 7264
Atlas_Id 52892
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143612618 and ends at 143617562 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EEF1D (8q24.3) / TSTA3 (8q24.3)EEF1D 8q24.3 / TSTA3 8q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  EEF1D/TSTA3 (8q24)

External links

Nomenclature
HGNC (Hugo)TSTA3   12390
Cards
Entrez_Gene (NCBI)TSTA3  7264  tissue specific transplantation antigen P35B
AliasesFX; P35B; SDR4E1
GeneCards (Weizmann)TSTA3
Ensembl hg19 (Hinxton)ENSG00000104522 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104522 [Gene_View]  ENSG00000104522 [Sequence]  chr8:143612618-143617562 [Contig_View]  TSTA3 [Vega]
ICGC DataPortalENSG00000104522
TCGA cBioPortalTSTA3
AceView (NCBI)TSTA3
Genatlas (Paris)TSTA3
WikiGenes7264
SOURCE (Princeton)TSTA3
Genetics Home Reference (NIH)TSTA3
Genomic and cartography
GoldenPath hg38 (UCSC)TSTA3  -     chr8:143612618-143617562 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSTA3  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathTSTA3 - 8q24.3 [CytoView hg19]  TSTA3 - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000104522
Mapping of homologs : NCBITSTA3 [Mapview hg19]  TSTA3 [Mapview hg38]
OMIM137020   
Gene and transcription
Genbank (Entrez)AK096752 AK303125 AK313560 BC001941 BC093061
RefSeq transcript (Entrez)NM_001317783 NM_003313
RefSeq genomic (Entrez)NC_000008 NT_187571
Consensus coding sequences : CCDS (NCBI)TSTA3
Cluster EST : UnigeneHs.404119 [ NCBI ]
CGAP (NCI)Hs.404119
Alternative Splicing GalleryENSG00000104522
Gene ExpressionTSTA3 [ NCBI-GEO ]   TSTA3 [ EBI - ARRAY_EXPRESS ]   TSTA3 [ SEEK ]   TSTA3 [ MEM ]
Gene Expression Viewer (FireBrowse)TSTA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7264
GTEX Portal (Tissue expression)TSTA3
Human Protein AtlasENSG00000104522-TSTA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13630   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13630  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13630
Splice isoforms : SwissVarQ13630
Catalytic activity : Enzyme1.1.1.271 [ Enzyme-Expasy ]   1.1.1.2711.1.1.271 [ IntEnz-EBI ]   1.1.1.271 [ BRENDA ]   1.1.1.271 [ KEGG ]   
PhosPhoSitePlusQ13630
Domains : Interpro (EBI)Epimerase_deHydtase    GDP_fucose/colitose_synth    NAD(P)-bd_dom_sf   
Domain families : Pfam (Sanger)Epimerase (PF01370)   
Domain families : Pfam (NCBI)pfam01370   
Conserved Domain (NCBI)TSTA3
DMDM Disease mutations7264
Blocks (Seattle)TSTA3
PDB (RSDB)4B8W    4B8Z    4BKP    4BL5    4E5Y   
PDB Europe4B8W    4B8Z    4BKP    4BL5    4E5Y   
PDB (PDBSum)4B8W    4B8Z    4BKP    4BL5    4E5Y   
PDB (IMB)4B8W    4B8Z    4BKP    4BL5    4E5Y   
Structural Biology KnowledgeBase4B8W    4B8Z    4BKP    4BL5    4E5Y   
SCOP (Structural Classification of Proteins)4B8W    4B8Z    4BKP    4BL5    4E5Y   
CATH (Classification of proteins structures)4B8W    4B8Z    4BKP    4BL5    4E5Y   
SuperfamilyQ13630
Human Protein Atlas [tissue]ENSG00000104522-TSTA3 [tissue]
Peptide AtlasQ13630
HPRD00654
IPIIPI00014361   IPI00909958   IPI00981359   IPI01012947   IPI00984362   IPI00980982   IPI00982011   
Protein Interaction databases
DIP (DOE-UCLA)Q13630
IntAct (EBI)Q13630
FunCoupENSG00000104522
BioGRIDTSTA3
STRING (EMBL)TSTA3
ZODIACTSTA3
Ontologies - Pathways
QuickGOQ13630
Ontology : AmiGOT cell mediated cytotoxicity  cytosol  leukocyte cell-cell adhesion  electron transfer activity  GDP-mannose metabolic process  electron transport chain  'de novo' GDP-L-fucose biosynthetic process  'de novo' GDP-L-fucose biosynthetic process  'de novo' GDP-L-fucose biosynthetic process  GDP-4-dehydro-D-rhamnose reductase activity  identical protein binding  GDP-mannose 3,5-epimerase activity  GDP-L-fucose synthase activity  GDP-L-fucose synthase activity  coenzyme binding  extracellular exosome  
Ontology : EGO-EBIT cell mediated cytotoxicity  cytosol  leukocyte cell-cell adhesion  electron transfer activity  GDP-mannose metabolic process  electron transport chain  'de novo' GDP-L-fucose biosynthetic process  'de novo' GDP-L-fucose biosynthetic process  'de novo' GDP-L-fucose biosynthetic process  GDP-4-dehydro-D-rhamnose reductase activity  identical protein binding  GDP-mannose 3,5-epimerase activity  GDP-L-fucose synthase activity  GDP-L-fucose synthase activity  coenzyme binding  extracellular exosome  
Pathways : KEGGFructose and mannose metabolism    Amino sugar and nucleotide sugar metabolism   
NDEx NetworkTSTA3
Atlas of Cancer Signalling NetworkTSTA3
Wikipedia pathwaysTSTA3
Orthology - Evolution
OrthoDB7264
GeneTree (enSembl)ENSG00000104522
Phylogenetic Trees/Animal Genes : TreeFamTSTA3
HOGENOMQ13630
Homologs : HomoloGeneTSTA3
Homology/Alignments : Family Browser (UCSC)TSTA3
Gene fusions - Rearrangements
Fusion : MitelmanEEF1D/TSTA3 [8q24.3/8q24.3]  [t(8;8)(q24;q24)]  
Fusion PortalEEF1D 8q24.3 TSTA3 8q24.3 LUAD
Fusion : QuiverTSTA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSTA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSTA3
dbVarTSTA3
ClinVarTSTA3
1000_GenomesTSTA3 
Exome Variant ServerTSTA3
ExAC (Exome Aggregation Consortium)ENSG00000104522
GNOMAD BrowserENSG00000104522
Varsome BrowserTSTA3
Genetic variants : HAPMAP7264
Genomic Variants (DGV)TSTA3 [DGVbeta]
DECIPHERTSTA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSTA3 
Mutations
ICGC Data PortalTSTA3 
TCGA Data PortalTSTA3 
Broad Tumor PortalTSTA3
OASIS PortalTSTA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSTA3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSTA3
Mutations and Diseases : HGMDTSTA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSTA3
DgiDB (Drug Gene Interaction Database)TSTA3
DoCM (Curated mutations)TSTA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSTA3 (select a term)
intoGenTSTA3
Cancer3DTSTA3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137020   
Orphanet
DisGeNETTSTA3
MedgenTSTA3
Genetic Testing Registry TSTA3
NextProtQ13630 [Medical]
TSGene7264
GENETestsTSTA3
Target ValidationTSTA3
Huge Navigator TSTA3 [HugePedia]
snp3D : Map Gene to Disease7264
BioCentury BCIQTSTA3
ClinGenTSTA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7264
Chemical/Pharm GKB GenePA37056
Clinical trialTSTA3
Miscellaneous
canSAR (ICR)TSTA3 (select the gene name)
DataMed IndexTSTA3
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSTA3
EVEXTSTA3
GoPubMedTSTA3
iHOPTSTA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:13:29 CET 2019
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