TTC12 (tetratricopeptide repeat domain 12)

2007-12-01 Affiliation

Identity

HGNC

TTC12

LOCATION

11q23.2

LOCUSID

54970

ALIAS

CILD45,TPARM

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54970
MIM: 610732
HGNC: 23700
Ensembl: ENSG00000149292

Variants:

dbSNP: 54970
ClinVar: 54970
TCGA: ENSG00000149292
COSMIC: TTC12

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000149292	ENST00000314756	Q9H892
ENSG00000149292	ENST00000314756	B0YJB4
ENSG00000149292	ENST00000393020	A8MTE9
ENSG00000149292	ENST00000429951	C9JYU1
ENSG00000149292	ENST00000442859	C9J1D2
ENSG00000149292	ENST00000455306	C9JPY5
ENSG00000149292	ENST00000462711	H0YEF6
ENSG00000149292	ENST00000464224	E9PP06
ENSG00000149292	ENST00000483239	J3KR69
ENSG00000149292	ENST00000494714	Q9H892
ENSG00000149292	ENST00000494714	B0YJB4
ENSG00000149292	ENST00000524580	E9PIB6
ENSG00000149292	ENST00000525965	E9PKU6
ENSG00000149292	ENST00000527362	H0YDB4
ENSG00000149292	ENST00000529221	Q9H892
ENSG00000149292	ENST00000529221	A8K8G6
ENSG00000149292	ENST00000529850	E9PJI9
ENSG00000149292	ENST00000531164	E9PIS6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
17085484	2006	Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.	82
17761687	2007	Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.	51
17761687	2007	Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.	51
18828801	2008	Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.	41
18828801	2008	Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.	41
21168125	2011	TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.	37
23303482	2013	ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure.	26
20133381	2010	Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.	7
20133381	2010	Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.	7
17657212	2007	Hypermethylation of TTC12 gene in acute lymphoblastic leukemia.	2

Citation

Dessen P

TTC12 (tetratricopeptide repeat domain 12)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49940/ttc12