Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91875
HGNC: 19274
Ensembl: ENSG00000136319
Variants:
dbSNP: 91875
ClinVar: 91875
TCGA: ENSG00000136319
COSMIC: TTC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136319 | ENST00000258821 | Q8N0Z6 |
| ENSG00000136319 | ENST00000383029 | H9KV81 |
| ENSG00000136319 | ENST00000553828 | G3V3I6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35670379 | 2022 | TTC5 syndrome: Clinical and molecular spectrum of a severe and recognizable condition. | 3 |
| 35670379 | 2022 | TTC5 syndrome: Clinical and molecular spectrum of a severe and recognizable condition. | 3 |
| 32439809 | 2021 | Bi-allelic TTC5 variants cause delayed developmental milestones and intellectual disability. | 2 |
| 34947995 | 2021 | Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer. | 3 |
| 32439809 | 2021 | Bi-allelic TTC5 variants cause delayed developmental milestones and intellectual disability. | 2 |
| 34947995 | 2021 | Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer. | 3 |
| 31727855 | 2020 | TTC5 mediates autoregulation of tubulin via mRNA degradation. | 47 |
| 31727855 | 2020 | TTC5 mediates autoregulation of tubulin via mRNA degradation. | 47 |
| 31648166 | 2019 | TRIP13 interference inhibits the proliferation and metastasis of thyroid cancer cells through regulating TTC5/p53 pathway and epithelial-mesenchymal transition related genes expression. | 2 |
| 31648166 | 2019 | TRIP13 interference inhibits the proliferation and metastasis of thyroid cancer cells through regulating TTC5/p53 pathway and epithelial-mesenchymal transition related genes expression. | 2 |
| 23559008 | 2013 | TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells. | 6 |
| 24091941 | 2013 | Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. | 3 |
| 23559008 | 2013 | TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells. | 6 |
| 24091941 | 2013 | Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. | 3 |
| 21147850 | 2011 | Regulation of glucocorticoid receptor activity by a stress responsive transcriptional cofactor. | 15 |
Citation
Dessen P
TTC5 (tetratricopeptide repeat domain 5)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50198/ttc5
