Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7272
MIM: 604092
HGNC: 12401
Ensembl: ENSG00000112742
Variants:
dbSNP: 7272
ClinVar: 7272
TCGA: ENSG00000112742
COSMIC: TTK
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell cycle | KEGG | ko04110 |
| Cell cycle | KEGG | hsa04110 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37815894 | 2023 | TTK is a potential regulator of tumor progression correlated with dedifferentiation and immune cell infiltration in papillary thyroid cancer. | 0 |
| 37894942 | 2023 | CWH43 Is a Novel Tumor Suppressor Gene with Negative Regulation of TTK in Colorectal Cancer. | 1 |
| 37815894 | 2023 | TTK is a potential regulator of tumor progression correlated with dedifferentiation and immune cell infiltration in papillary thyroid cancer. | 0 |
| 37894942 | 2023 | CWH43 Is a Novel Tumor Suppressor Gene with Negative Regulation of TTK in Colorectal Cancer. | 1 |
| 34767669 | 2022 | Hsp90 regulates the tumorigenic function of tyrosine protein kinase in osteosarcoma. | 3 |
| 34846157 | 2022 | TTK predicts triple positive breast cancer prognosis and regulates tumor proliferation and invasion. | 6 |
| 35850753 | 2022 | TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma. | 4 |
| 34767669 | 2022 | Hsp90 regulates the tumorigenic function of tyrosine protein kinase in osteosarcoma. | 3 |
| 34846157 | 2022 | TTK predicts triple positive breast cancer prognosis and regulates tumor proliferation and invasion. | 6 |
| 35850753 | 2022 | TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma. | 4 |
| 33627787 | 2021 | Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. | 18 |
| 34187556 | 2021 | Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis. | 8 |
| 34266426 | 2021 | Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway. | 1 |
| 34456216 | 2021 | Frequent expression of a novel cancer testis antigen, protein kinase human monopolar spindle 1 (hMps1/TTK) in human urinary bladder transitional cell carcinoma. | 1 |
| 34516342 | 2021 | TTK (threonine tyrosine kinase) regulates the malignant behaviors of cancer cells and is regulated by microRNA-582-5p in ovarian cancer. | 7 |
Citation
Dessen P
TTK (TTK protein kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42725/ttk
