Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TUBGCP2 (tubulin gamma complex associated protein 2)

Identity

Alias_namestubulin, gamma complex associated protein 2
Alias_symbol (synonym)GCP2
Spc97p
SPBC97
Other aliasALP4
GCP-2
Grip103
PAMDDFS
SPC97
h103p
hGCP2
hSpc97
HGNC (Hugo) TUBGCP2
LocusID (NCBI) 10844
Atlas_Id 75372
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 133278630 and ends at 133309156 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM155A (13q33.3) / TUBGCP2 (10q26.3)SGMS1 (10q11.23) / TUBGCP2 (10q26.3)TUBGCP2 (10q26.3) / UBE4A (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(10;11)(q26;q23) TUBGCP2/UBE4A
t(10;13)(q26;q33) FAM155A/TUBGCP2

External links

Nomenclature
HGNC (Hugo)TUBGCP2   18599
Cards
Entrez_Gene (NCBI)TUBGCP2  10844  tubulin gamma complex associated protein 2
AliasesALP4; GCP-2; GCP2; Grip103; 
PAMDDFS; SPBC97; SPC97; Spc97p; h103p; hGCP2; hSpc97
GeneCards (Weizmann)TUBGCP2
Ensembl hg19 (Hinxton)ENSG00000130640 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130640 [Gene_View]  ENSG00000130640 [Sequence]  chr10:133278630-133309156 [Contig_View]  TUBGCP2 [Vega]
ICGC DataPortalENSG00000130640
TCGA cBioPortalTUBGCP2
AceView (NCBI)TUBGCP2
Genatlas (Paris)TUBGCP2
WikiGenes10844
SOURCE (Princeton)TUBGCP2
Genetics Home Reference (NIH)TUBGCP2
Genomic and cartography
GoldenPath hg38 (UCSC)TUBGCP2  -     chr10:133278630-133309156 -  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUBGCP2  -     10q26.3   [Description]    (hg19-Feb_2009)
GoldenPathTUBGCP2 - 10q26.3 [CytoView hg19]  TUBGCP2 - 10q26.3 [CytoView hg38]
ImmunoBaseENSG00000130640
genome Data Viewer NCBITUBGCP2 [Mapview hg19]  
OMIM617817   618737   
Gene and transcription
Genbank (Entrez)AA377890 AF042379 AK092113 AK096087 AK128430
RefSeq transcript (Entrez)NM_001256617 NM_001256618 NM_006659
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUBGCP2
Alternative Splicing GalleryENSG00000130640
Gene ExpressionTUBGCP2 [ NCBI-GEO ]   TUBGCP2 [ EBI - ARRAY_EXPRESS ]   TUBGCP2 [ SEEK ]   TUBGCP2 [ MEM ]
Gene Expression Viewer (FireBrowse)TUBGCP2 [ Firebrowse - Broad ]
GenevisibleExpression of TUBGCP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10844
GTEX Portal (Tissue expression)TUBGCP2
Human Protein AtlasENSG00000130640-TUBGCP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BSJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BSJ2
Splice isoforms : SwissVarQ9BSJ2
PhosPhoSitePlusQ9BSJ2
Domains : Interpro (EBI)GCP    GCP_C    GCP_N   
Domain families : Pfam (Sanger)GCP_C_terminal (PF04130)    GCP_N_terminal (PF17681)   
Domain families : Pfam (NCBI)pfam04130    pfam17681   
Conserved Domain (NCBI)TUBGCP2
DMDM Disease mutations10844
Blocks (Seattle)TUBGCP2
SuperfamilyQ9BSJ2
Human Protein Atlas [tissue]ENSG00000130640-TUBGCP2 [tissue]
Peptide AtlasQ9BSJ2
HPRD18245
IPIIPI00029705   IPI01008898   IPI00922855   IPI00384183   IPI00980579   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSJ2
IntAct (EBI)Q9BSJ2
FunCoupENSG00000130640
BioGRIDTUBGCP2
STRING (EMBL)TUBGCP2
ZODIACTUBGCP2
Ontologies - Pathways
QuickGOQ9BSJ2
Ontology : AmiGOmitotic cell cycle  spindle pole  equatorial microtubule organizing center  gamma-tubulin complex  protein binding  nucleoplasm  centrosome  centrosome  microtubule organizing center  cytosol  cytoplasmic microtubule  microtubule nucleation  gamma-tubulin small complex  membrane  cytoplasmic microtubule organization  gamma-tubulin binding  microtubule minus-end binding  spindle assembly  meiotic cell cycle  microtubule nucleation by interphase microtubule organizing center  protein-containing complex assembly  
Ontology : EGO-EBImitotic cell cycle  spindle pole  equatorial microtubule organizing center  gamma-tubulin complex  protein binding  nucleoplasm  centrosome  centrosome  microtubule organizing center  cytosol  cytoplasmic microtubule  microtubule nucleation  gamma-tubulin small complex  membrane  cytoplasmic microtubule organization  gamma-tubulin binding  microtubule minus-end binding  spindle assembly  meiotic cell cycle  microtubule nucleation by interphase microtubule organizing center  protein-containing complex assembly  
NDEx NetworkTUBGCP2
Atlas of Cancer Signalling NetworkTUBGCP2
Wikipedia pathwaysTUBGCP2
Orthology - Evolution
OrthoDB10844
GeneTree (enSembl)ENSG00000130640
Phylogenetic Trees/Animal Genes : TreeFamTUBGCP2
HOGENOMQ9BSJ2
Homologs : HomoloGeneTUBGCP2
Homology/Alignments : Family Browser (UCSC)TUBGCP2
Gene fusions - Rearrangements
Fusion : QuiverTUBGCP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUBGCP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUBGCP2
dbVarTUBGCP2
ClinVarTUBGCP2
1000_GenomesTUBGCP2 
Exome Variant ServerTUBGCP2
GNOMAD BrowserENSG00000130640
Varsome BrowserTUBGCP2
Genetic variants : HAPMAP10844
Genomic Variants (DGV)TUBGCP2 [DGVbeta]
DECIPHERTUBGCP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUBGCP2 
Mutations
ICGC Data PortalTUBGCP2 
TCGA Data PortalTUBGCP2 
Broad Tumor PortalTUBGCP2
OASIS PortalTUBGCP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUBGCP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTUBGCP2
Mutations and Diseases : HGMDTUBGCP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUBGCP2
DgiDB (Drug Gene Interaction Database)TUBGCP2
DoCM (Curated mutations)TUBGCP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUBGCP2 (select a term)
intoGenTUBGCP2
Cancer3DTUBGCP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617817    618737   
Orphanet
DisGeNETTUBGCP2
MedgenTUBGCP2
Genetic Testing Registry TUBGCP2
NextProtQ9BSJ2 [Medical]
TSGene10844
GENETestsTUBGCP2
Target ValidationTUBGCP2
Huge Navigator TUBGCP2 [HugePedia]
snp3D : Map Gene to Disease10844
BioCentury BCIQTUBGCP2
ClinGenTUBGCP2
Clinical trials, drugs, therapy
Protein Interactions : CTD10844
Pharm GKB GenePA38598
Clinical trialTUBGCP2
Miscellaneous
canSAR (ICR)TUBGCP2 (select the gene name)
HarmonizomeTUBGCP2
DataMed IndexTUBGCP2
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUBGCP2
EVEXTUBGCP2
GoPubMedTUBGCP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 10 20:42:54 CEST 2020
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