Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11334
MIM: 607052
HGNC: 17034
Ensembl: ENSG00000114383
Variants:
dbSNP: 11334
ClinVar: 11334
TCGA: ENSG00000114383
COSMIC: TUSC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000114383 | ENST00000232496 | O75896 |
| ENSG00000114383 | ENST00000417867 | G3V0I0 |
| ENSG00000114383 | ENST00000421918 | F2Z2A9 |
| ENSG00000114383 | ENST00000454201 | F2Z2A9 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35167936 | 2022 | NEDD4 degrades TUSC2 to promote glioblastoma progression. | 3 |
| 35167936 | 2022 | NEDD4 degrades TUSC2 to promote glioblastoma progression. | 3 |
| 31973107 | 2020 | The TUSC2 Tumour Suppressor Inhibits the Malignant Phenotype of Human Thyroid Cancer Cells via SMAC/DIABLO Protein. | 11 |
| 31973107 | 2020 | The TUSC2 Tumour Suppressor Inhibits the Malignant Phenotype of Human Thyroid Cancer Cells via SMAC/DIABLO Protein. | 11 |
| 30896880 | 2019 | MicroRNA‑663b downregulation inhibits proliferation and induces apoptosis in bladder cancer cells by targeting TUSC2. | 3 |
| 31481748 | 2019 | MicroRNA-138 is a Prognostic Biomarker for Triple-Negative Breast Cancer and Promotes Tumorigenesis via TUSC2 repression. | 21 |
| 30896880 | 2019 | MicroRNA‑663b downregulation inhibits proliferation and induces apoptosis in bladder cancer cells by targeting TUSC2. | 3 |
| 31481748 | 2019 | MicroRNA-138 is a Prognostic Biomarker for Triple-Negative Breast Cancer and Promotes Tumorigenesis via TUSC2 repression. | 21 |
| 30219035 | 2018 | TUSC2P suppresses the tumor function of esophageal squamous cell carcinoma by regulating TUSC2 expression and correlates with disease prognosis. | 10 |
| 30219035 | 2018 | TUSC2P suppresses the tumor function of esophageal squamous cell carcinoma by regulating TUSC2 expression and correlates with disease prognosis. | 10 |
| 27661106 | 2016 | TWIST1/miR-584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells. | 16 |
| 27845352 | 2016 | TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. | 15 |
| 27661106 | 2016 | TWIST1/miR-584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells. | 16 |
| 27845352 | 2016 | TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. | 15 |
| 26053020 | 2015 | Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy. | 19 |
Citation
Dessen P
TUSC2 (tumor suppressor 2, mitochondrial calcium regulator)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42731/tusc2
