TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific)

2015-03-01  

Identity

HGNC
LOCATION
11q12.3
LOCUSID
ALIAS
PAPD2,RBM21,STARPAP,TENT1,TUTase,URLC6
FUSION GENES

Other Information

Locus ID:

NCBI: 64852
MIM: 610641
HGNC: 26184
Ensembl: ENSG00000255508

Variants:

dbSNP: 64852
ClinVar: 64852
TCGA: ENSG00000255508
COSMIC: TUT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255508ENST00000496634H3BRB1

References

Pubmed IDYearTitleCitations
182881972008A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.115
222443302012Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.35
211024102010The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.28
183051082008CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs.27
238749772013The human TUT1 nucleotidyl transferase as a global regulator of microRNA abundance.16
233060792013The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs.13
289110962017Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.11
285899552017Crystal structures of U6 snRNA-specific terminal uridylyltransferase.10
234169772014Star-PAP controls HPV E6 regulation of p53 and sensitizes cells to VP-16.9
264969452016CstF-64 and 3'-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα.8

Citation

Dessen P

TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55133/tut1