TUT4 (terminal uridylyl transferase 4)

2007-02-01  

Identity

HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
PAPD3,TENT3A,ZCCHC11

Other Information

Locus ID:

NCBI: 23318
MIM: 613692
HGNC: 28981
Ensembl: ENSG00000134744

Variants:

dbSNP: 23318
ClinVar: 23318
TCGA: ENSG00000134744
COSMIC: TUT4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134744ENST00000257177A0A0C4DFM7
ENSG00000134744ENST00000355809X6R5G7
ENSG00000134744ENST00000371544Q5TAX3
ENSG00000134744ENST00000470626E9PQS7
ENSG00000134744ENST00000471623H0YDZ6
ENSG00000134744ENST00000473856E9PRG2
ENSG00000134744ENST00000474453H0YDJ1
ENSG00000134744ENST00000484723E9PKX1
ENSG00000134744ENST00000494469H0YF28
ENSG00000134744ENST00000524582E9PJN7
ENSG00000134744ENST00000527941H0YEY0
ENSG00000134744ENST00000528457H0YCX5
ENSG00000134744ENST00000528642E9PKY2
ENSG00000134744ENST00000531722H0YEE8

References

Pubmed IDYearTitleCitations
197033962009TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation.361
197033962009TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation.361
197011942009Zcchc11-dependent uridylation of microRNA directs cytokine expression.126
230636542012Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.124
228989842012Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).89
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
254802992014Uridylation by TUT4 and TUT7 marks mRNA for degradation.79
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
240569622014miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis.31
261148922015Identification of small molecule inhibitors of Zcchc11 TUTase activity.17

Citation

Dessen P

TUT4 (terminal uridylyl transferase 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/50017/tut4