TXNL1 (thioredoxin like 1)

2011-11-01  

Identity

HGNC
LOCATION
18q21.31
LOCUSID
ALIAS
HEL-S-114,TRP32,TXL-1,TXNL,Txl
FUSION GENES

Other Information

Locus ID:

NCBI: 9352
MIM: 603049
HGNC: 12436
Ensembl: ENSG00000091164

Variants:

dbSNP: 9352
ClinVar: 9352
TCGA: ENSG00000091164
COSMIC: TXNL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000091164ENST00000217515O43396
ENSG00000091164ENST00000217515V9HW51
ENSG00000091164ENST00000586262K7ER96
ENSG00000091164ENST00000587613K7EML9
ENSG00000091164ENST00000587807K7EPB7
ENSG00000091164ENST00000589329K7EKG2
ENSG00000091164ENST00000589931K7EME7
ENSG00000091164ENST00000590954O43396
ENSG00000091164ENST00000590954V9HW51

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
193492772009Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome.27
245257312014TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.27
245257312014TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.27
193492802009Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.15
233622752013Thioredoxin-related protein 32 (TRP32) specifically reduces oxidized phosphatase of regenerating liver (PRL).10
179871242007The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.7
212901632011HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.6
162313152006Expression of a thioredoxin-related protein-1 is induced by prostaglandin E(2).3
204552722010Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.2

Citation

Dessen P

TXNL1 (thioredoxin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-11-01

Online version: http://atlasgeneticsoncology.org/gene/52491/txnl1