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TXNRD1 (thioredoxin reductase 1)

Identity

Alias_symbol (synonym)TXNR
GRIM-12
Trxr1
Other aliasTR
TR1
TRXR1
HGNC (Hugo) TXNRD1
LocusID (NCBI) 7296
Atlas_Id 46587
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 104286682 and ends at 104350307 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CHST11 (12q23.3) / TXNRD1 (12q23.3)MAP7D1 (1p34.3) / TXNRD1 (12q23.3)SRSF11 (1p31.1) / TXNRD1 (12q23.3)
TXNRD1 (12q23.3) / ADGRD1 (12q24.33)TXNRD1 (12q23.3) / CHST11 (12q23.3)TXNRD1 (12q23.3) / HCFC2 (12q23.3)
TXNRD1 (12q23.3) / LCN2 (9q34.11)TXNRD1 (12q23.3) / NPM1 (5q35.1)TXNRD1 (12q23.3) / RNF185 (22q12.2)
TXNRD1 (12q23.3) / UIMC1 (5q35.2)TXNRD1 (12q23.3) / USP30 (12q24.11)TXNRD1 12q23.3 / HCFC2 12q23.3
TXNRD1 12q23.3 / USP30 12q24.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]

Solid Tumors TranslocLungAdenocarcID6751 TT_t1212q23q23ID101385 TT_t1212q23q24ID101403 TT_t1212q23q24ID101404 TT_t1212q23q24ID6804


External links

Nomenclature
HGNC (Hugo)TXNRD1   12437
Cards
Entrez_Gene (NCBI)TXNRD1  7296  thioredoxin reductase 1
AliasesGRIM-12; TR; TR1; TRXR1; 
TXNR
GeneCards (Weizmann)TXNRD1
Ensembl hg19 (Hinxton)ENSG00000198431 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198431 [Gene_View]  ENSG00000198431 [Sequence]  chr12:104286682-104350307 [Contig_View]  TXNRD1 [Vega]
ICGC DataPortalENSG00000198431
TCGA cBioPortalTXNRD1
AceView (NCBI)TXNRD1
Genatlas (Paris)TXNRD1
WikiGenes7296
SOURCE (Princeton)TXNRD1
Genetics Home Reference (NIH)TXNRD1
Genomic and cartography
GoldenPath hg38 (UCSC)TXNRD1  -     chr12:104286682-104350307 +  12q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TXNRD1  -     12q23.3   [Description]    (hg19-Feb_2009)
GoldenPathTXNRD1 - 12q23.3 [CytoView hg19]  TXNRD1 - 12q23.3 [CytoView hg38]
ImmunoBaseENSG00000198431
Mapping of homologs : NCBITXNRD1 [Mapview hg19]  TXNRD1 [Mapview hg38]
OMIM601112   
Gene and transcription
Genbank (Entrez)AF077367 AF208018 AI097548 AJ001050 AK128515
RefSeq transcript (Entrez)NM_001093771 NM_001261445 NM_001261446 NM_003330 NM_182729 NM_182742 NM_182743
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TXNRD1
Alternative Splicing GalleryENSG00000198431
Gene ExpressionTXNRD1 [ NCBI-GEO ]   TXNRD1 [ EBI - ARRAY_EXPRESS ]   TXNRD1 [ SEEK ]   TXNRD1 [ MEM ]
Gene Expression Viewer (FireBrowse)TXNRD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)7296
GTEX Portal (Tissue expression)TXNRD1
Human Protein AtlasENSG00000198431-TXNRD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TXNRD1
DMDM Disease mutations7296
Blocks (Seattle)TXNRD1
Human Protein Atlas [tissue]ENSG00000198431-TXNRD1 [tissue]
HPRD03068
IPIIPI00983068   IPI00871867   IPI00783641   IPI00847482   IPI00554786   IPI00885213   IPI00984188   IPI00983539   IPI00981495   IPI00985249   IPI00984681   IPI00982356   IPI00977771   IPI00979993   IPI00983604   IPI00979268   IPI00981644   IPI00977989   
Protein Interaction databases
FunCoupENSG00000198431
BioGRIDTXNRD1
STRING (EMBL)TXNRD1
ZODIACTXNRD1
Ontologies - Pathways
Huge Navigator TXNRD1 [HugePedia]
snp3D : Map Gene to Disease7296
BioCentury BCIQTXNRD1
ClinGenTXNRD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7296
Chemical/Pharm GKB GenePA37093
Clinical trialTXNRD1
Miscellaneous
canSAR (ICR)TXNRD1 (select the gene name)
DataMed IndexTXNRD1
Probes
Litterature
PubMed149 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTXNRD1
EVEXTXNRD1
GoPubMedTXNRD1
iHOPTXNRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Feb 19 17:15:02 CET 2020

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