UBE2E2 (ubiquitin conjugating enzyme E2 E2)

2007-04-01  

Identity

HGNC
LOCATION
3p24.3
LOCUSID
ALIAS
UBCH8
FUSION GENES

Other Information

Locus ID:

NCBI: 7325
MIM: 602163
HGNC: 12478
Ensembl: ENSG00000182247

Variants:

dbSNP: 7325
ClinVar: 7325
TCGA: ENSG00000182247
COSMIC: UBE2E2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182247ENST00000335798F8W8F0
ENSG00000182247ENST00000396703Q96LR5
ENSG00000182247ENST00000396703A0A024R2Q2
ENSG00000182247ENST00000425792Q96LR5
ENSG00000182247ENST00000425792A0A024R2Q2
ENSG00000182247ENST00000452894C9J180
ENSG00000182247ENST00000613545A0A087X283
ENSG00000182247ENST00000628311F8WF15

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367650412023UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.1
367650412023UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.1
278630922017Associations between changes in the maternal gut microbiome and differentially methylated regions of diabetes-associated genes in fetuses: A pilot study from a birth cohort study.9
279185342017Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.74
278630922017Associations between changes in the maternal gut microbiome and differentially methylated regions of diabetes-associated genes in fetuses: A pilot study from a birth cohort study.9
279185342017Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.74
271756652016Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.5
272812732016Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.18
271756652016Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.5
272812732016Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.18
260200622015Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han population.5
260200622015Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han population.5
253377792014Lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population.3
253377792014Lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population.3
238625832013Putative association between UBE2E2 polymorphisms and the risk of gestational diabetes mellitus.2

Citation

Dessen P

UBE2E2 (ubiquitin conjugating enzyme E2 E2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47212/ube2e2