Atlas of Genetics and Cytogenetics in Oncology and Haematology

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UBE2F (ubiquitin conjugating enzyme E2 F (putative))

Identity

Alias_namesubiquitin-conjugating enzyme E2F (putative)
Alias_symbol (synonym)NCE2
Other alias
HGNC (Hugo) UBE2F
LocusID (NCBI) 140739
Atlas_Id 47077
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 237966945 and ends at 238042782 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AGAP1 (2q37.2) / UBE2F (2q37.3)NGFRAP1 () / UBE2F (2q37.3)UBE2F (2q37.3) / C20orf194 (20p13)
AGAP1 2q37.2 / UBE2F 2q37.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  AGAP1/UBE2F (2q37)

External links

Nomenclature
HGNC (Hugo)UBE2F   12480
Cards
Entrez_Gene (NCBI)UBE2F  140739  ubiquitin conjugating enzyme E2 F (putative)
AliasesNCE2
GeneCards (Weizmann)UBE2F
Ensembl hg19 (Hinxton)ENSG00000184182 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184182 [Gene_View]  ENSG00000184182 [Sequence]  chr2:237966945-238042782 [Contig_View]  UBE2F [Vega]
ICGC DataPortalENSG00000184182
TCGA cBioPortalUBE2F
AceView (NCBI)UBE2F
Genatlas (Paris)UBE2F
WikiGenes140739
SOURCE (Princeton)UBE2F
Genetics Home Reference (NIH)UBE2F
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2F  -     chr2:237966945-238042782 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2F  -     2q37.3   [Description]    (hg19-Feb_2009)
GoldenPathUBE2F - 2q37.3 [CytoView hg19]  UBE2F - 2q37.3 [CytoView hg38]
Genome Data Viewer NCBIUBE2F [Mapview hg19]  
OMIM617700   
Gene and transcription
Genbank (Entrez)AF310723 AK290063 AK293334 AK294107 AK297502
RefSeq transcript (Entrez)NM_001278305 NM_001278306 NM_001278307 NM_001278308 NM_080678
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2F
Alternative Splicing GalleryENSG00000184182
Gene ExpressionUBE2F [ NCBI-GEO ]   UBE2F [ EBI - ARRAY_EXPRESS ]   UBE2F [ SEEK ]   UBE2F [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2F [ Firebrowse - Broad ]
GenevisibleExpression of UBE2F in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140739
GTEX Portal (Tissue expression)UBE2F
Human Protein AtlasENSG00000184182-UBE2F [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969M7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969M7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969M7
Splice isoforms : SwissVarQ969M7
PhosPhoSitePlusQ969M7
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2F
DMDM Disease mutations140739
PDB (RSDB)2EDI    3FN1    4GBA   
PDB Europe2EDI    3FN1    4GBA   
PDB (PDBSum)2EDI    3FN1    4GBA   
PDB (IMB)2EDI    3FN1    4GBA   
Structural Biology KnowledgeBase2EDI    3FN1    4GBA   
SCOP (Structural Classification of Proteins)2EDI    3FN1    4GBA   
CATH (Classification of proteins structures)2EDI    3FN1    4GBA   
SuperfamilyQ969M7
Human Protein Atlas [tissue]ENSG00000184182-UBE2F [tissue]
Peptide AtlasQ969M7
HPRD14812
IPIIPI00056432   IPI00910610   IPI00908717   IPI00917266   IPI00909362   IPI00917903   IPI00917801   IPI00917512   IPI00916053   IPI00915920   IPI00916820   IPI00916680   IPI00916420   IPI00917130   IPI00916946   IPI00916839   IPI00916389   IPI00916293   
Protein Interaction databases
DIP (DOE-UCLA)Q969M7
IntAct (EBI)Q969M7
FunCoupENSG00000184182
BioGRIDUBE2F
STRING (EMBL)UBE2F
ZODIACUBE2F
Ontologies - Pathways
QuickGOQ969M7
Ontology : AmiGOprotein polyubiquitination  protein binding  ATP binding  nucleus  cytosol  protein ubiquitination  NEDD8 transferase activity  NEDD8 transferase activity  post-translational protein modification  protein neddylation  protein neddylation  protein neddylation  ubiquitin conjugating enzyme activity  NEDD8 conjugating enzyme activity  
Ontology : EGO-EBIprotein polyubiquitination  protein binding  ATP binding  nucleus  cytosol  protein ubiquitination  NEDD8 transferase activity  NEDD8 transferase activity  post-translational protein modification  protein neddylation  protein neddylation  protein neddylation  ubiquitin conjugating enzyme activity  NEDD8 conjugating enzyme activity  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2F
Atlas of Cancer Signalling NetworkUBE2F
Wikipedia pathwaysUBE2F
Orthology - Evolution
OrthoDB140739
GeneTree (enSembl)ENSG00000184182
Phylogenetic Trees/Animal Genes : TreeFamUBE2F
HOGENOMQ969M7
Homologs : HomoloGeneUBE2F
Homology/Alignments : Family Browser (UCSC)UBE2F
Gene fusions - Rearrangements
Fusion : MitelmanAGAP1/UBE2F [2q37.2/2q37.3]  
Fusion PortalAGAP1 2q37.2 UBE2F 2q37.3 HNSC
Fusion : QuiverUBE2F
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2F [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2F
dbVarUBE2F
ClinVarUBE2F
1000_GenomesUBE2F 
Exome Variant ServerUBE2F
GNOMAD BrowserENSG00000184182
Varsome BrowserUBE2F
Genetic variants : HAPMAP140739
Genomic Variants (DGV)UBE2F [DGVbeta]
DECIPHERUBE2F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2F 
Mutations
ICGC Data PortalUBE2F 
TCGA Data PortalUBE2F 
Broad Tumor PortalUBE2F
OASIS PortalUBE2F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2F  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUBE2F
Mutations and Diseases : HGMDUBE2F
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect UBE2F
DgiDB (Drug Gene Interaction Database)UBE2F
DoCM (Curated mutations)UBE2F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2F (select a term)
intoGenUBE2F
Cancer3DUBE2F (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617700   
Orphanet
DisGeNETUBE2F
MedgenUBE2F
Genetic Testing Registry UBE2F
NextProtQ969M7 [Medical]
TSGene140739
GENETestsUBE2F
Open Targets GeneticsENSG00000184182  [validation]
snp3D : Map Gene to Disease140739
BioCentury BCIQUBE2F
ClinGenUBE2F
Clinical trials, drugs, therapy
Protein Interactions : CTD140739
Pharm GKB GenePA37130
Clinical trialUBE2F
Miscellaneous
canSAR (ICR)UBE2F (select the gene name)
HarmonizomeUBE2F
DataMed IndexUBE2F
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2F
EVEXUBE2F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 20:17:29 CEST 2020
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