| Nomenclature | | HGNC (Hugo) | UBE2L3 12488 |
| Entrez_Gene (NCBI) | UBE2L3 7332 ubiquitin-conjugating enzyme E2L 3 |
| Cards | | GeneCards (Weizmann) | UBE2L3 |
| Ensembl (Hinxton) | ENSG00000185651 [Gene_View] chr22:21903736-21978323 [Contig_View] UBE2L3 [Vega] |
| AceView (NCBI) | UBE2L3 |
| Genatlas (Paris) | UBE2L3 |
| SOURCE (Stanford) | NM_001256355 NM_001256356 NM_003347 NM_198157 |
| Genomic and cartography | | GoldenPath (UCSC) | UBE2L3 - 22q11.21 chr22:21903736-21978323 + 22q11.21 [Description] (hg19-Feb_2009) |
| Ensembl | UBE2L3 - 22q11.21 [CytoView] |
| Mapping of homologs : NCBI | UBE2L3 [Mapview] |
| OMIM | 603721 |
| Gene and transcription |
| Genbank (Entrez) | AJ000519 AK125396 AK291083 AK293179 AK299985 |
| RefSeq transcript (SRS) | NM_001256355 NM_001256356 NM_003347 NM_198157 |
| RefSeq transcript (Entrez) | NM_001256355 NM_001256356 NM_003347 NM_198157 |
| RefSeq genomic (SRS) | AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112 |
| RefSeq genomic (Entrez) | AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112 |
| Consensus coding sequences : CCDS (NCBI) | UBE2L3 |
| Cluster EST : Unigene | Hs.108104 [ SRS ] Hs.108104 [ NCBI ] |
| CGAP (NCI) | Hs.108104 |
| Alternative Splicing : Fast-db (Paris) | GSHG0019859 |
| Alternative Splicing Gallery | ENSG00000185651 |
| Gene Expression | UBE2L3 [ NCBI-GEO ] UBE2L3 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P68036 (SRS) P68036 (Uniprot) |
| NextProt | P68036 |
| With graphics : InterPro | P68036 |
| Splice isoforms : SwissVar | P68036(Swissvar) |
| Domaine pattern : Prosite (SRS) | UBIQUITIN_CONJUGAT_1 (PS00183) UBIQUITIN_CONJUGAT_2 (PS50127) |
| Domaine pattern : Prosite (Expaxy) | UBIQUITIN_CONJUGAT_1 (PS00183) UBIQUITIN_CONJUGAT_2 (PS50127) |
| Domains : Interpro (SRS) | UBQ-conjugat_E2 UBQ-conjugating_AS UBQ-conjugating_enzyme/RWD |
| Domains : Interpro (EBI) | UBQ-conjugat_E2 UBQ-conjugating_AS UBQ-conjugating_enzyme/RWD |
| Related proteins : CluSTr | P68036 |
| Domain families : Pfam (SRS) | UQ_con (PF00179) |
| Domain families : Pfam (Sanger) | UQ_con (PF00179) |
| Domain families : Pfam (NCBI) | pfam00179 |
| DMDM | 7332 |
| Blocks (Seattle) | P68036 |
| PDB (SRS) | 1C4Z 1FBV 3SQV 3SY2 |
| PDB (PDBSum) | 1C4Z 1FBV 3SQV 3SY2 |
| PDB (IMB) | 1C4Z 1FBV 3SQV 3SY2 |
| PDB (RSDB) | 1C4Z 1FBV 3SQV 3SY2 |
| Human Protein Atlas | ENSG00000185651 |
| HPRD | 04762 |
| IPI | IPI00021347 IPI00909975 IPI00909773 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P68036 |
| IntAct (EBI) | P68036 |
| FunCoup | ENSG00000185651 |
| REACTOME | UBE2L3 |
| Protein Interaction Database | 7332 |
| BioGRID | UBE2L3 |
| InParanoid | P68036 |
| Interologous Interaction database | P68036 |
| IntegromeDB | UBE2L3 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | UBE2L3 |
| SNP (GeneSNP Utah) | UBE2L3 |
| SNP : HGBase | UBE2L3 |
| Genetic variants : HAPMAP | UBE2L3 |
| Somatic Mutations in Cancer : COSMIC | UBE2L3 |
| CONAN: Copy Number Analysis | UBE2L3 |
| Mutations and Diseases : HGMD | UBE2L3 |
| OMIM | 603721 |
| GENETests | 603721 |
| Disease Genetic Association | UBE2L3 |
| Huge Navigator |
UBE2L3 [HugePedia] UBE2L3 [HugeCancerGEM] |
| Genomic Variants | UBE2L3 UBE2L3 [DGVbeta] |
| snp3D : Map Gene to Disease | 7332 |
| General knowledge |
|---|
| Homologs : HomoloGene | UBE2L3 |
| Homology/Alignments : Family Browser (UCSC) | UBE2L3 |
| Phylogenetic Trees/Animal Genes : TreeFam | UBE2L3 |
| Catalytic activity : Enzyme | 6.3.2.19 [ Enzyme-Expasy ] 6.3.2.19 [ Enzyme-SRS ] 6.3.2.19 [ IntEnz-EBI ] 6.3.2.19 [ BRENDA ] 6.3.2.19 [ KEGG ] |
| Chemical/Protein Interactions : CTD | 7332 |
| Chemical/Pharm GKB Gene | PA37137 |
| Clinical trial | UBE2L3 |
| Cancer Resource (Charite) | ENSG00000185651 |
| Ontology : AmiGO | ubiquitin ligase complex protein polyubiquitination transcription coactivator activity ubiquitin-protein ligase activity ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm transcription, DNA-dependent regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent cellular protein modification process ubiquitin-dependent protein catabolic process regulation of S phase of mitotic cell cycle cell proliferation protein ubiquitination enzyme binding ubiquitin protein ligase binding protein K11-linked ubiquitination cellular response to steroid hormone stimulus cellular response to glucocorticoid stimulus |
| Ontology : EGO-EBI | ubiquitin ligase complex protein polyubiquitination transcription coactivator activity ubiquitin-protein ligase activity ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm transcription, DNA-dependent regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent cellular protein modification process ubiquitin-dependent protein catabolic process regulation of S phase of mitotic cell cycle cell proliferation protein ubiquitination enzyme binding ubiquitin protein ligase binding protein K11-linked ubiquitination cellular response to steroid hormone stimulus cellular response to glucocorticoid stimulus |
| Pathways : KEGG | Parkinson's disease |
| Other databases | | Probes |
|---|
| Litterature | | PubMed | 151 Pubmed reference(s) in Entrez |
| PubGene | UBE2L3 |
| iHOP | UBE2L3 |
