Identity
HGNC
LOCATION
12q22
LOCUSID
ALIAS
HEL-S-71,UBC13,UBCHBEN,
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7334
MIM: 603679
HGNC: 12492
Ensembl: ENSG00000177889
Variants:
dbSNP: 7334
ClinVar: 7334
TCGA: ENSG00000177889
COSMIC: UBE2N
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38715121 | 2024 | UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells. | 0 |
| 38715121 | 2024 | UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells. | 0 |
| 36822329 | 2023 | SET7 methylates the deubiquitinase OTUB1 at Lys (122) to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis. | 5 |
| 36822329 | 2023 | SET7 methylates the deubiquitinase OTUB1 at Lys (122) to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis. | 5 |
| 35263148 | 2022 | Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. | 11 |
| 35263148 | 2022 | Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. | 11 |
| 33288957 | 2021 | Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler. | 18 |
| 33650289 | 2021 | Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor. | 7 |
| 34160887 | 2021 | The lncRNA 'UCA1' modulates the response to chemotherapy of ovarian cancer through direct binding to miR-27a-5p and control of UBE2N levels. | 17 |
| 33288957 | 2021 | Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler. | 18 |
| 33650289 | 2021 | Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor. | 7 |
| 34160887 | 2021 | The lncRNA 'UCA1' modulates the response to chemotherapy of ovarian cancer through direct binding to miR-27a-5p and control of UBE2N levels. | 17 |
| 32196955 | 2020 | Inhibiting ubiquitin conjugating enzyme E2 N by microRNA-590-3p reduced cell growth of cervical carcinoma. | 8 |
| 32265276 | 2020 | Ubc13-Mms2 cooperates with a family of RING E3 proteins in budding yeast membrane protein sorting. | 8 |
| 32398758 | 2020 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. | 14 |
Citation
Dessen P
UBE2N (ubiquitin conjugating enzyme E2 N)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42752/ube2n
