UCP3 (uncoupling protein 3)

2007-02-01  

Identity

HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
SLC25A9

Other Information

Locus ID:

NCBI: 7352
MIM: 602044
HGNC: 12519
Ensembl: ENSG00000175564

Variants:

dbSNP: 7352
ClinVar: 7352
TCGA: ENSG00000175564
COSMIC: UCP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175564ENST00000314032P55916
ENSG00000175564ENST00000314032A0A0S2Z4G5
ENSG00000175564ENST00000426995P55916
ENSG00000175564ENST00000544614F5H3N5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Mitochondrial Uncoupling ProteinsREACTOMER-HSA-166187
The fatty acid cycling modelREACTOMER-HSA-167826
The proton buffering modelREACTOMER-HSA-167827

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380581672024Human mitochondrial uncoupling protein 3 functions as a metabolite transporter.1
380581672024Human mitochondrial uncoupling protein 3 functions as a metabolite transporter.1
366517112023Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease.2
368100172023The influence of six polymorphisms of uncoupling protein 3 (UCP3) gene and childhood obesity: a case-control study.0
366517112023Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease.2
368100172023The influence of six polymorphisms of uncoupling protein 3 (UCP3) gene and childhood obesity: a case-control study.0
350204962022Association of UCP3 Polymorphisms with Nonalcoholic Steatohepatitis and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease Brazilian Patients.2
361407802022Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia.1
350204962022Association of UCP3 Polymorphisms with Nonalcoholic Steatohepatitis and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease Brazilian Patients.2
361407802022Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia.1
335352042021Effect of -55C/T Polymorphism of Uncoupling Protein 3 Gene on Risk for New-Onset Diabetes in Chinese Peritoneal Dialysis Patients: A Prospective Cohort Study.0
347127302021Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis.2
335352042021Effect of -55C/T Polymorphism of Uncoupling Protein 3 Gene on Risk for New-Onset Diabetes in Chinese Peritoneal Dialysis Patients: A Prospective Cohort Study.0
347127302021Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis.2
318999152020Association of UCP1, UCP2 and UCP3 gene polymorphisms with cardiovascular disease risk factors in European adolescents: the HELENA study.0

Citation

Dessen P

UCP3 (uncoupling protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43772/ucp3