UGT3A1 (UDP glycosyltransferase family 3 member A1)

2014-11-01  

Identity

HGNC
UGT3A1
LOCATION
5p13.2
LOCUSID
133688
ALIAS
-

Other Information

Locus ID:

NCBI: 133688
MIM: 616383
HGNC: 26625
Ensembl: ENSG00000145626

Variants:

dbSNP: 133688
ClinVar: 133688
TCGA: ENSG00000145626
COSMIC: UGT3A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145626ENST00000274278Q6NUS8
ENSG00000145626ENST00000274278A8K444
ENSG00000145626ENST00000333811Q6NUS8
ENSG00000145626ENST00000333811A0A024R085
ENSG00000145626ENST00000503189B7Z8Q8
ENSG00000145626ENST00000507113E9PD17
ENSG00000145626ENST00000515801D6RHV6
ENSG00000145626ENST00000625798Q6NUS8
ENSG00000145626ENST00000625798A0A024R085

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
GlucuronidationREACTOMER-HSA-156588

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
189811712008Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.18
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
198146572010UGT3A: novel UDP-glycosyltransferases of the UGT superfamily.8
226219302012Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes.6

Citation

Dessen P

UGT3A1 (UDP glycosyltransferase family 3 member A1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75474/ugt3a1