Identity
HGNC
LOCATION
12q24.33
LOCUSID
ALIAS
ATG1,ATG1A,UNC51,Unc51.1,hATG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8408
MIM: 603168
HGNC: 12558
Ensembl: ENSG00000177169
Variants:
dbSNP: 8408
ClinVar: 8408
TCGA: ENSG00000177169
COSMIC: ULK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177169 | ENST00000321867 | O75385 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37731335 | 2024 | AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis. | 1 |
| 38039841 | 2024 | Role of CircCHD2 in the pathogenesis of gestational diabetes mellitus by regulating autophagy via miR-33b-3p/ULK1 axis. | 1 |
| 38135696 | 2024 | SPHK1 potentiates colorectal cancer progression and metastasis via regulating autophagy mediated by TRAF6-induced ULK1 ubiquitination. | 1 |
| 38286802 | 2024 | Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer. | 2 |
| 38324636 | 2024 | DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser(56) to diminish pancreatic β cell function upon overnutrition. | 0 |
| 38459884 | 2024 | RNF135 promotes cell proliferation and autophagy in lung adenocarcinoma by promoting the phosphorylation of ULK1. | 0 |
| 38517447 | 2024 | Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway. | 0 |
| 38617533 | 2024 | IL-33 Accelerates Chronic Atrophic Gastritis through AMPK-ULK1 Axis Mediated Autolysosomal Degradation of GKN1. | 0 |
| 37731335 | 2024 | AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis. | 1 |
| 38039841 | 2024 | Role of CircCHD2 in the pathogenesis of gestational diabetes mellitus by regulating autophagy via miR-33b-3p/ULK1 axis. | 1 |
| 38135696 | 2024 | SPHK1 potentiates colorectal cancer progression and metastasis via regulating autophagy mediated by TRAF6-induced ULK1 ubiquitination. | 1 |
| 38286802 | 2024 | Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer. | 2 |
| 38324636 | 2024 | DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser(56) to diminish pancreatic β cell function upon overnutrition. | 0 |
| 38459884 | 2024 | RNF135 promotes cell proliferation and autophagy in lung adenocarcinoma by promoting the phosphorylation of ULK1. | 0 |
| 38517447 | 2024 | Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway. | 0 |
Citation
Dessen P
ULK1 (unc-51 like autophagy activating kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43551/ulk1
