Identity
HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
UNC5H2,p53RDL1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 219699
MIM: 607870
HGNC: 12568
Ensembl: ENSG00000107731
Variants:
dbSNP: 219699
ClinVar: 219699
TCGA: ENSG00000107731
COSMIC: UNC5B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107731 | ENST00000335350 | Q8IZJ1 |
| ENSG00000107731 | ENST00000373192 | Q8IZJ1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38156865 | 2023 | Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma. | 0 |
| 38156865 | 2023 | Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma. | 0 |
| 35974411 | 2022 | Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis. | 4 |
| 35974411 | 2022 | Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis. | 4 |
| 33345442 | 2021 | The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells. | 2 |
| 33706585 | 2021 | Long non-coding RNA PITPNA-AS1 regulates UNC5B expression in papillary thyroid cancer via sponging miR-129-5p. | 2 |
| 34239689 | 2021 | UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway. | 11 |
| 34381052 | 2021 | A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. | 12 |
| 34470826 | 2021 | Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity. | 7 |
| 33345442 | 2021 | The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells. | 2 |
| 33706585 | 2021 | Long non-coding RNA PITPNA-AS1 regulates UNC5B expression in papillary thyroid cancer via sponging miR-129-5p. | 2 |
| 34239689 | 2021 | UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway. | 11 |
| 34381052 | 2021 | A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. | 12 |
| 34470826 | 2021 | Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity. | 7 |
| 31769036 | 2020 | Netrin-1 and its receptor Unc5b as markers of periodontal disease. | 2 |
Citation
Dessen P
UNC5B (unc-5 netrin receptor B)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46461/unc5b
