UPK1A (uroplakin 1A)

2007-02-01  

Identity

HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
TSPAN21,UP1A,UPIA,UPKA

Other Information

Locus ID:

NCBI: 11045
MIM: 611557
HGNC: 12577
Ensembl: ENSG00000105668

Variants:

dbSNP: 11045
ClinVar: 11045
TCGA: ENSG00000105668
COSMIC: UPK1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105668ENST00000222275O00322
ENSG00000105668ENST00000379013O00322
ENSG00000105668ENST00000616789O00322
ENSG00000105668ENST00000617999O00322

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
152004082004Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.18
195775752009Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: implications in transmembrane signaling transduction.17
209781962010Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma.15
246989992014Reduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.6
120364482002High expression of human uroplakin Ia in urinary bladder transitional cell carcinoma.4
159138092005Transcriptional control of the human urothelial-specific gene, uroplakin Ia.1
251973752014Decreased expression of uroplakin Ia is associated with colorectal cancer progression and poor survival of patients.1
257014632015Downregulation of UPK1A suppresses proliferation and enhances apoptosis of bladder transitional cell carcinoma cells.0

Citation

Dessen P

UPK1A (uroplakin 1A)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45725/upk1a