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UPK2 (uroplakin 2)

Identity

Alias_symbol (synonym)UP2
UPII
MGC138598
Other alias
HGNC (Hugo) UPK2
LocusID (NCBI) 7379
Atlas_Id 51556
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 118956298 and ends at 118958559 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UPK2   12579
Cards
Entrez_Gene (NCBI)UPK2  7379  uroplakin 2
AliasesUP2; UPII
GeneCards (Weizmann)UPK2
Ensembl hg19 (Hinxton)ENSG00000110375 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110375 [Gene_View]  ENSG00000110375 [Sequence]  chr11:118956298-118958559 [Contig_View]  UPK2 [Vega]
ICGC DataPortalENSG00000110375
TCGA cBioPortalUPK2
AceView (NCBI)UPK2
Genatlas (Paris)UPK2
WikiGenes7379
SOURCE (Princeton)UPK2
Genetics Home Reference (NIH)UPK2
Genomic and cartography
GoldenPath hg38 (UCSC)UPK2  -     chr11:118956298-118958559 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UPK2  -     11q23.3   [Description]    (hg19-Feb_2009)
GoldenPathUPK2 - 11q23.3 [CytoView hg19]  UPK2 - 11q23.3 [CytoView hg38]
ImmunoBaseENSG00000110375
Mapping of homologs : NCBIUPK2 [Mapview hg19]  UPK2 [Mapview hg38]
OMIM611558   
Gene and transcription
Genbank (Entrez)AB009454 AF000562 AY455312 BC113900 CD556028
RefSeq transcript (Entrez)NM_006760
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UPK2
Cluster EST : UnigeneHs.379613 [ NCBI ]
CGAP (NCI)Hs.379613
Alternative Splicing GalleryENSG00000110375
Gene ExpressionUPK2 [ NCBI-GEO ]   UPK2 [ EBI - ARRAY_EXPRESS ]   UPK2 [ SEEK ]   UPK2 [ MEM ]
Gene Expression Viewer (FireBrowse)UPK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7379
GTEX Portal (Tissue expression)UPK2
Human Protein AtlasENSG00000110375-UPK2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00526   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00526  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00526
Splice isoforms : SwissVarO00526
PhosPhoSitePlusO00526
Domains : Interpro (EBI)Uroplakin-2   
Domain families : Pfam (Sanger)Uroplakin_II (PF07353)   
Domain families : Pfam (NCBI)pfam07353   
Domain structure : Prodom (Prabi Lyon)Uroplakin_II (PD022112)   
Conserved Domain (NCBI)UPK2
DMDM Disease mutations7379
Blocks (Seattle)UPK2
SuperfamilyO00526
Human Protein Atlas [tissue]ENSG00000110375-UPK2 [tissue]
Peptide AtlasO00526
HPRD10295
IPIIPI00012113   IPI00985312   
Protein Interaction databases
DIP (DOE-UCLA)O00526
IntAct (EBI)O00526
FunCoupENSG00000110375
BioGRIDUPK2
STRING (EMBL)UPK2
ZODIACUPK2
Ontologies - Pathways
QuickGOO00526
Ontology : AmiGOprotein binding  integral component of plasma membrane  multicellular organism development  apical plasma membrane  epithelial cell differentiation  epithelial cell differentiation  extracellular exosome  
Ontology : EGO-EBIprotein binding  integral component of plasma membrane  multicellular organism development  apical plasma membrane  epithelial cell differentiation  epithelial cell differentiation  extracellular exosome  
NDEx NetworkUPK2
Atlas of Cancer Signalling NetworkUPK2
Wikipedia pathwaysUPK2
Orthology - Evolution
OrthoDB7379
GeneTree (enSembl)ENSG00000110375
Phylogenetic Trees/Animal Genes : TreeFamUPK2
HOGENOMO00526
Homologs : HomoloGeneUPK2
Homology/Alignments : Family Browser (UCSC)UPK2
Gene fusions - Rearrangements
Fusion : QuiverUPK2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUPK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UPK2
dbVarUPK2
ClinVarUPK2
1000_GenomesUPK2 
Exome Variant ServerUPK2
ExAC (Exome Aggregation Consortium)ENSG00000110375
GNOMAD BrowserENSG00000110375
Varsome BrowserUPK2
Genetic variants : HAPMAP7379
Genomic Variants (DGV)UPK2 [DGVbeta]
DECIPHERUPK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUPK2 
Mutations
ICGC Data PortalUPK2 
TCGA Data PortalUPK2 
Broad Tumor PortalUPK2
OASIS PortalUPK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUPK2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUPK2
Mutations and Diseases : HGMDUPK2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UPK2
DgiDB (Drug Gene Interaction Database)UPK2
DoCM (Curated mutations)UPK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UPK2 (select a term)
intoGenUPK2
Cancer3DUPK2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611558   
Orphanet
DisGeNETUPK2
MedgenUPK2
Genetic Testing Registry UPK2
NextProtO00526 [Medical]
TSGene7379
GENETestsUPK2
Target ValidationUPK2
Huge Navigator UPK2 [HugePedia]
snp3D : Map Gene to Disease7379
BioCentury BCIQUPK2
ClinGenUPK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7379
Chemical/Pharm GKB GenePA37211
Clinical trialUPK2
Miscellaneous
canSAR (ICR)UPK2 (select the gene name)
DataMed IndexUPK2
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUPK2
EVEXUPK2
GoPubMedUPK2
iHOPUPK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jan 27 15:12:37 CET 2020

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