UPRT (uracil phosphoribosyltransferase homolog)

2009-08-01  

Identity

HGNC
UPRT
LOCATION
Xq13.3
LOCUSID
139596
ALIAS
FUR1,UPP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 139596
MIM: 300656
HGNC: 28334
Ensembl: ENSG00000094841

Variants:

dbSNP: 139596
ClinVar: 139596
TCGA: ENSG00000094841
COSMIC: UPRT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000094841ENST00000373373F8W6E9
ENSG00000094841ENST00000373379A0A0A0MRR5
ENSG00000094841ENST00000373383Q96BW1
ENSG00000094841ENST00000373383A8KAF9
ENSG00000094841ENST00000462237Q96BW1
ENSG00000094841ENST00000530743E9PSD7
ENSG00000094841ENST00000652605A0A494C0H3

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Pyrimidine metabolismKEGGko00240
Pyrimidine metabolismKEGGhsa00240
Metabolic pathwaysKEGGhsa01100

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
173849012007Identification and characterization of human uracil phosphoribosyltransferase (UPRTase).8
186265082009Specific targeting of prostate cancer cells in vitro by the suicide gene/prodrug system, uracil phosphoribosyltransferase/5-fluorouracil, under the control of prostate-specific membrane antigen promoter/enhancer.3

Citation

Dessen P

UPRT (uracil phosphoribosyltransferase homolog)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51032/uprt