USP17L9P (ubiquitin specific peptidase 17 like family member 9, pseudogene)

2010-05-01  

Identity

HGNC
USP17L9P
LOCATION
4p16.1
LOCUSID
391627
ALIAS
RS447,USP17,USP17A,USP17H,USP17I,USP17J,USP17K,USP17L,USP17M

Other Information

Locus ID:

NCBI: 391627
MIM: 607011
HGNC: 12615
Ensembl: ENSG00000251694

Variants:

dbSNP: 391627
ClinVar: 391627
TCGA: ENSG00000251694
COSMIC: USP17L9P

RNA/Proteins

References

Pubmed IDYearTitleCitations
250708932014The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor γt (RORγt) in Th17 cells.21
212394942011Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.17
266104882015The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33.12
201472982010The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.11
226622182012Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity.11
241343112014A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17.9
252021222014USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response.9
286709582017USP17 is upregulated in osteosarcoma and promotes cell proliferation, metastasis, and epithelial-mesenchymal transition through stabilizing SMAD4.9
308545652019De-ubiquitination of ELK-1 by USP17 potentiates mitogenic gene expression and cell proliferation.4
304091802018USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells.2

Citation

Dessen P

USP17L9P (ubiquitin specific peptidase 17 like family member 9, pseudogene)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51462/usp17l9p