USP35 (ubiquitin specific peptidase 35)

2014-11-01  

Identity

HGNC
USP35
LOCATION
11q14.1
LOCUSID
57558
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57558
HGNC: 20061
Ensembl: ENSG00000118369

Variants:

dbSNP: 57558
ClinVar: 57558
TCGA: ENSG00000118369
COSMIC: USP35

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118369ENST00000526425Q9P2H5
ENSG00000118369ENST00000528910E9PRM2
ENSG00000118369ENST00000529308Q9P2H5
ENSG00000118369ENST00000530267E9PK78
ENSG00000118369ENST00000530546H0YEP1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
259155642015Deubiquitinating enzymes regulate PARK2-mediated mitophagy.41
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
263482042015USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2.9
294496772018USP35 regulates mitotic progression by modulating the stability of Aurora B.6
296858922018Expansion of DUB functionality generated by alternative isoforms - USP35, a case study.3

Citation

Dessen P

USP35 (ubiquitin specific peptidase 35)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75558/usp35