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USP36 (ubiquitin specific peptidase 36)

Identity

Alias_namesubiquitin specific protease 36
Alias_symbol (synonym)KIAA1453
FLJ12851
Other aliasDUB1
HGNC (Hugo) USP36
LocusID (NCBI) 57602
Atlas_Id 50353
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 78795652 and ends at 78840527 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CYTH1 (17q25.3) / USP36 (17q25.3)MED26 (19p13.11) / USP36 (17q25.3)USP36 (17q25.3) / CYTH1 (17q25.3)
USP36 (17q25.3) / OFCC1 (6p24.3)USP36 (17q25.3) / USP36 (17q25.3)CYTH1 17q25.3 / USP36 17q25.3
USP36 17q25.3 / OFCC1 6p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(6;17)(p24;q25) USP36/OFCC1
CYTH1/USP36 (17q25)


External links

Nomenclature
HGNC (Hugo)USP36   20062
Cards
Entrez_Gene (NCBI)USP36  57602  ubiquitin specific peptidase 36
AliasesDUB1
GeneCards (Weizmann)USP36
Ensembl hg19 (Hinxton)ENSG00000055483 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000055483 [Gene_View]  ENSG00000055483 [Sequence]  chr17:78795652-78840527 [Contig_View]  USP36 [Vega]
ICGC DataPortalENSG00000055483
TCGA cBioPortalUSP36
AceView (NCBI)USP36
Genatlas (Paris)USP36
WikiGenes57602
SOURCE (Princeton)USP36
Genetics Home Reference (NIH)USP36
Genomic and cartography
GoldenPath hg38 (UCSC)USP36  -     chr17:78795652-78840527 -  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP36  -     17q25.3   [Description]    (hg19-Feb_2009)
GoldenPathUSP36 - 17q25.3 [CytoView hg19]  USP36 - 17q25.3 [CytoView hg38]
ImmunoBaseENSG00000055483
Mapping of homologs : NCBIUSP36 [Mapview hg19]  USP36 [Mapview hg38]
OMIM612543   
Gene and transcription
Genbank (Entrez)AB040886 AK001671 AK022840 AK022913 AK023077
RefSeq transcript (Entrez)NM_001321291 NM_025090
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP36
Cluster EST : UnigeneHs.464243 [ NCBI ]
CGAP (NCI)Hs.464243
Alternative Splicing GalleryENSG00000055483
Gene ExpressionUSP36 [ NCBI-GEO ]   USP36 [ EBI - ARRAY_EXPRESS ]   USP36 [ SEEK ]   USP36 [ MEM ]
Gene Expression Viewer (FireBrowse)USP36 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57602
GTEX Portal (Tissue expression)USP36
Human Protein AtlasENSG00000055483-USP36 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P275   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P275  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P275
Splice isoforms : SwissVarQ9P275
PhosPhoSitePlusQ9P275
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP36
DMDM Disease mutations57602
Blocks (Seattle)USP36
SuperfamilyQ9P275
Human Protein Atlas [tissue]ENSG00000055483-USP36 [tissue]
Peptide AtlasQ9P275
HPRD07164
IPIIPI00843790   IPI00001786   IPI00902886   IPI01013999   IPI00383547   
Protein Interaction databases
DIP (DOE-UCLA)Q9P275
IntAct (EBI)Q9P275
FunCoupENSG00000055483
BioGRIDUSP36
STRING (EMBL)USP36
ZODIACUSP36
Ontologies - Pathways
QuickGOQ9P275
Ontology : AmiGORNA binding  cysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleolus  cytoplasm  ubiquitin-dependent protein catabolic process  nucleolus organization  nucleolus organization  negative regulation of macroautophagy  histone deubiquitination  protein deubiquitination  protein deubiquitination  protein deubiquitination  nuclear speck  regulation of protein stability  regulation of apoptotic process  protein stabilization  regulation of autophagy of mitochondrion  positive regulation of protein targeting to mitochondrion  regulation of rRNA processing  regulation of rRNA processing  
Ontology : EGO-EBIRNA binding  cysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleolus  cytoplasm  ubiquitin-dependent protein catabolic process  nucleolus organization  nucleolus organization  negative regulation of macroautophagy  histone deubiquitination  protein deubiquitination  protein deubiquitination  protein deubiquitination  nuclear speck  regulation of protein stability  regulation of apoptotic process  protein stabilization  regulation of autophagy of mitochondrion  positive regulation of protein targeting to mitochondrion  regulation of rRNA processing  regulation of rRNA processing  
NDEx NetworkUSP36
Atlas of Cancer Signalling NetworkUSP36
Wikipedia pathwaysUSP36
Orthology - Evolution
OrthoDB57602
GeneTree (enSembl)ENSG00000055483
Phylogenetic Trees/Animal Genes : TreeFamUSP36
HOGENOMQ9P275
Homologs : HomoloGeneUSP36
Homology/Alignments : Family Browser (UCSC)USP36
Gene fusions - Rearrangements
Fusion : MitelmanCYTH1/USP36 [17q25.3/17q25.3]  [t(17;17)(q25;q25)]  
Fusion : MitelmanUSP36/OFCC1 [17q25.3/6p24.3]  [t(6;17)(p24;q25)]  
Fusion PortalCYTH1 17q25.3 USP36 17q25.3 LUAD
Fusion PortalUSP36 17q25.3 OFCC1 6p24.3 BRCA
Fusion : QuiverUSP36
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP36 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP36
dbVarUSP36
ClinVarUSP36
1000_GenomesUSP36 
Exome Variant ServerUSP36
ExAC (Exome Aggregation Consortium)ENSG00000055483
GNOMAD BrowserENSG00000055483
Varsome BrowserUSP36
Genetic variants : HAPMAP57602
Genomic Variants (DGV)USP36 [DGVbeta]
DECIPHERUSP36 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP36 
Mutations
ICGC Data PortalUSP36 
TCGA Data PortalUSP36 
Broad Tumor PortalUSP36
OASIS PortalUSP36 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP36  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUSP36
Mutations and Diseases : HGMDUSP36
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP36
DgiDB (Drug Gene Interaction Database)USP36
DoCM (Curated mutations)USP36 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP36 (select a term)
intoGenUSP36
Cancer3DUSP36(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612543   
Orphanet
DisGeNETUSP36
MedgenUSP36
Genetic Testing Registry USP36
NextProtQ9P275 [Medical]
TSGene57602
GENETestsUSP36
Target ValidationUSP36
Huge Navigator USP36 [HugePedia]
snp3D : Map Gene to Disease57602
BioCentury BCIQUSP36
ClinGenUSP36
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57602
Chemical/Pharm GKB GenePA134949090
Clinical trialUSP36
Miscellaneous
canSAR (ICR)USP36 (select the gene name)
DataMed IndexUSP36
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP36
EVEXUSP36
GoPubMedUSP36
iHOPUSP36
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:14:38 CET 2019

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