VAT1 (vesicle amine transport 1)

2014-06-01  

Identity

HGNC
VAT1
LOCATION
17q21.31
LOCUSID
10493
ALIAS
VATI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10493
MIM: 604631
HGNC: 16919
Ensembl: ENSG00000108828

Variants:

dbSNP: 10493
ClinVar: 10493
TCGA: ENSG00000108828
COSMIC: VAT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108828ENST00000355653Q99536
ENSG00000108828ENST00000355653A0A024R1Z6
ENSG00000108828ENST00000420567Q99536
ENSG00000108828ENST00000587062K7ERT7
ENSG00000108828ENST00000587147K7ESA3
ENSG00000108828ENST00000587173Q99536
ENSG00000108828ENST00000589709K7ENX2
ENSG00000108828ENST00000589828K7ER81
ENSG00000108828ENST00000590924K7EM19
ENSG00000108828ENST00000592388K7EJM4

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208584612011An essential role for phospholipase D in the recruitment of vesicle amine transport protein-1 to membranes in human neutrophils.12
195084422009Vesicle amine transport protein-1 (VAT-1) is upregulated in glioblastomas and promotes migration.2
213947402011VAT-1 is a novel pathogenic factor of progressive benign prostatic hyperplasia.2

Citation

Dessen P

VAT1 (vesicle amine transport 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53948/vat1