Identity
HGNC
LOCATION
12q13.11
LOCUSID
ALIAS
NR1I1,PPP1R163
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7421
MIM: 601769
HGNC: 12679
Ensembl: ENSG00000111424
Variants:
dbSNP: 7421
ClinVar: 7421
TCGA: ENSG00000111424
COSMIC: VDR
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10239 | clodronate | Chemical | ClinicalAnnotation | associated | PD | 10692979, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA134687887 | selective beta-2-adrenoreceptor agonists | Chemical | ClinicalAnnotation | associated | PD | 15282200 | |
| PA164712563 | Bisphosphonates | Chemical | ClinicalAnnotation | associated | PD | 10692979, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA164712582 | calcium | Chemical | ClinicalAnnotation, VipGene | associated | PD | 15739035, 15861036, 17274004, 21418277, 9933478, 10692979, 10707958, 12162507, 12608943, 15739035, 15861036, 18443790, 19020788 | |
| PA164749390 | peginterferon alfa-2a | Chemical | ClinicalAnnotation | associated | PD | 25713999 | |
| PA164754789 | conjugated estrogens | Chemical | ClinicalAnnotation | associated | PD | 9860300 | |
| PA164760843 | deferasirox | Chemical | ClinicalAnnotation | associated | PD | 30651574 | |
| PA164784024 | peginterferon alfa-2b | Chemical | ClinicalAnnotation | associated | PD | ||
| PA165948902 | boceprevir | Chemical | MultilinkAnnotation | associated | 25836019 | ||
| PA166128365 | bone density | Disease | VipGene | associated | 15040830, 8970884, 10367030 | ||
| PA166154500 | rs731236 | Variant | VipGene | associated | 15739035, 17274004, 21418277, 9933478, 10707958 | ||
| PA166154516 | rs1544410 | Variant | VipGene | associated | 14685227, 16210379, 18470879, 20500803, 21651652, 9933478, 11450701 | ||
| PA166154531 | rs2228570 | Variant | VipGene | associated | 15739035, 15861036, 15864137, 17763859, 19647104, 20500803, 20716226, 21651652, 15295697 | ||
| PA166154592 | rs4516035 | Variant | VipGene | associated | 15864137, 15883634, 10320522 | ||
| PA166154608 | rs7975232 | Variant | VipGene | associated | |||
| PA166154640 | rs11568820 | Variant | VipGene | associated | 15864137, 15883634, 18827005, 20727239, 10320522 | ||
| PA166159389 | cryoglobulinemia | Disease | VariantAnnotation | associated | PD | 27139837 | |
| PA443250 | Acquired Immunodeficiency Syndrome | Disease | VipGene | associated | 15225772, 11679916 | ||
| PA443450 | Asthma | Disease | ClinicalAnnotation, VipGene | associated | PD | 15282200, 15282199, 15282200 | |
| PA443560 | Breast Neoplasms | Disease | VipGene | associated | 15328186, 16214913, 10680726 | ||
| PA443888 | Diabetes Mellitus, Type 1 | Disease | VipGene | associated | 10868975, 10792336 | ||
| PA444445 | Hepatitis C | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 25713999, 27139837 | |
| PA445019 | Myocardial Infarction | Disease | VipGene | associated | |||
| PA445172 | Osteitis Deformans | Disease | ClinicalAnnotation | associated | PD | 10692979, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA445190 | Osteoporosis | Disease | ClinicalAnnotation, VipGene | associated | PD | 8782780, 10692979, 11204438, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA445425 | Prostatic Neoplasms | Disease | VipGene | associated | |||
| PA445451 | Psoriasis | Disease | VipGene | associated | |||
| PA445566 | Rickets | Disease | VipGene | associated | |||
| PA445941 | Tuberculosis | Disease | VipGene | associated | 15141734, 15478069, 10696983 | ||
| PA446108 | Colorectal Neoplasms | Disease | ClinicalAnnotation | associated | PK | ||
| PA446432 | beta-Thalassemia | Disease | ClinicalAnnotation | associated | PD | 30651574 | |
| PA446863 | Hepatitis C, Chronic | Disease | ClinicalAnnotation | associated | PD | ||
| PA448082 | alendronate | Chemical | ClinicalAnnotation, VipGene | associated | PD | 14685227, 16210379, 18470879, 20500803, 21651652, 9933478, 10692979, 11450701, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA448714 | calcipotriol | Chemical | VipGene | associated | 15295697, 15739035, 15861036, 15864137, 17274004, 17763859, 19647104, 20500803, 20716226, 21418277, 21651652, 9933478, 10707958 | ||
| PA448717 | calcitriol | Chemical | VipGene | associated | 10707958, 11450701, 14685227, 15295697, 15739035, 15861036, 15864137, 15883634, 16210379, 17274004, 17763859, 18470879, 18827005, 19647104, 20500803, 20716226, 20727239, 21418277, 21651652, 333287, 9933478, 10320522 | ||
| PA449247 | dexamethasone | Chemical | VipGene | associated | 15864137, 15883634, 18827005, 20727239, 10320522 | ||
| PA449548 | etidronic acid | Chemical | ClinicalAnnotation | associated | PD | 10692979, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA450085 | irinotecan | Chemical | ClinicalAnnotation | associated | PK | ||
| PA450344 | medroxyprogesterone | Chemical | ClinicalAnnotation | associated | PD | 9860300 | |
| PA450496 | midazolam | Chemical | ClinicalAnnotation | associated | PK | ||
| PA451221 | raloxifene | Chemical | ClinicalAnnotation | associated | PD | 10692979, 12162507, 12608943, 15739035, 18443790, 19020788 | |
| PA451241 | ribavirin | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 25713999, 27139837 | |
| PA451899 | vitamin d and analogues | Chemical | VipGene | associated | 15739035, 15861036, 15864137, 17763859, 19647104, 20500803, 20716226, 21651652, 15295697 | ||
| PA451906 | warfarin | Chemical | ClinicalAnnotation | associated | PD | 29298995 | |
| PA451999 | interferons | Chemical | VariantAnnotation | associated | PD | 27139837 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36520094 | 2024 | Association of vitamin D receptor polymorphisms with cardiometabolic conditions in Pakistani population. | 0 |
| 37410265 | 2024 | Evolution of Vitamin D Status and Vitamin D Receptor Gene Expression Among Professional Handball Athletes During a Competitive Period. Relationship with Body Composition, Calcium, Magnesium and Phosphorous. | 0 |
| 37496429 | 2024 | Genetic association of vitamin D receptor gene with female infertility. | 0 |
| 37530048 | 2024 | Correlation of vitamin D receptor genotypes, specific IgE levels and other variables with asthma control in children. | 0 |
| 37824370 | 2024 | Frequency of Healthy Control Genotype of VDR Gene Polymorphisms in the Saudi Population of the Ha'il Region: A Comparative Study with Worldwide Population. | 1 |
| 38167474 | 2024 | Long pentraxin 3 and vitamin D receptor mRNA expression pattern of cumulus granulosa cells isolated from PCOS oocytes at different stages of nuclear maturation. | 0 |
| 38219064 | 2024 | Expression analysis of vitamin D receptor-associated long noncoding RNAs in patients with relapsing-remitting multiple sclerosis. | 0 |
| 38227018 | 2024 | Hypermethylation and down-regulation of vitamin D receptor (VDR) as contributing factors for polycystic ovary syndrome (PCOS): a case-control study from Kashmir, North India. | 1 |
| 38233797 | 2024 | The effect of BsmI (rs1544410) single nucleotide polymorphism of vitamin D receptor (VDR) on insulin resistance in healthy children and adolescents: a cross-sectional study. | 0 |
| 38258318 | 2024 | Role of VDR gene polymorphisms and vitamin D levels in normal and overweight patients with PCOS. | 0 |
| 38306913 | 2024 | Association between vitamin D receptor gene variants and neonatal sepsis: A systematic review and meta-analysis. | 0 |
| 38323352 | 2024 | BMP6 and VDR gene polymorphisms are associated with osteonecrosis in a sickle cell anaemia cohort. | 0 |
| 38339924 | 2024 | Relationship between vitamin D receptor genotypes (FOK1rs2228570) and IL18 gene expression in sample of multiple sclerosis Iraqi patients. | 0 |
| 38348498 | 2024 | Clinical and genetic determinants of vitamin D receptor expression in cutaneous melanoma patients. | 0 |
| 38397449 | 2024 | The Association of Vitamin D Receptor Gene Polymorphisms with Vitamin D, Total IgE, and Blood Eosinophils in Patients with Atopy. | 0 |
Citation
Dessen P
VDR (vitamin D receptor)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45741/vdr
