VGLL4 (vestigial like family member 4)

2011-12-01  

Identity

HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
VGL-4
FUSION GENES

Other Information

Locus ID:

NCBI: 9686
MIM: 618692
HGNC: 28966
Ensembl: ENSG00000144560

Variants:

dbSNP: 9686
ClinVar: 9686
TCGA: ENSG00000144560
COSMIC: VGLL4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144560ENST00000273038A0A075B6E4
ENSG00000144560ENST00000413604G5E9M9
ENSG00000144560ENST00000417206F8W708
ENSG00000144560ENST00000417466F8WBN7
ENSG00000144560ENST00000418000E7EQU6
ENSG00000144560ENST00000419541E7EUJ2
ENSG00000144560ENST00000424529Q14135
ENSG00000144560ENST00000424709C9JBN2
ENSG00000144560ENST00000426568A0A0A6YYI5
ENSG00000144560ENST00000430365G5E9M7
ENSG00000144560ENST00000437722C9JX59
ENSG00000144560ENST00000445411E7EWF5
ENSG00000144560ENST00000451674Q14135
ENSG00000144560ENST00000458499E7ERW0
ENSG00000144560ENST00000623028A0A096LP98
ENSG00000144560ENST00000638314A0A1W2PQQ9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366576372023VGLL4-TEAD1 promotes vascular smooth muscle cell differentiation from human pluripotent stem cells via TET2.2
366576372023VGLL4-TEAD1 promotes vascular smooth muscle cell differentiation from human pluripotent stem cells via TET2.2
331419982021The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells.7
335068982021LINC00641 regulates prostate cancer cell growth and apoptosis via the miR-365a-3p/VGLL4 axis.9
340040312021VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype.13
340756382021Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melanogaster and possible biological implications.4
343964252021HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway.5
331419982021The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells.7
335068982021LINC00641 regulates prostate cancer cell growth and apoptosis via the miR-365a-3p/VGLL4 axis.9
340040312021VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype.13
340756382021Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melanogaster and possible biological implications.4
343964252021HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway.5
303969962019Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion.26
317485082019VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer.6
303969962019Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion.26

Citation

Dessen P

VGLL4 (vestigial like family member 4)

Atlas Genet Cytogenet Oncol Haematol. 2011-12-01

Online version: http://atlasgeneticsoncology.org/gene/52512/vgll4