VOPP1 (VOPP1 WW domain binding protein)

2009-09-01  

Identity

HGNC
LOCATION
7p11.2
LOCUSID
ALIAS
ECOP,GASP,WBP1L2
FUSION GENES

Other Information

Locus ID:

NCBI: 81552
MIM: 611915
HGNC: 34518
Ensembl: ENSG00000154978

Variants:

dbSNP: 81552
ClinVar: 81552
TCGA: ENSG00000154978
COSMIC: VOPP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154978ENST00000285279Q96AW1
ENSG00000154978ENST00000414113C9JF99
ENSG00000154978ENST00000417399C9J548
ENSG00000154978ENST00000418904Q96AW1
ENSG00000154978ENST00000427700C9JVH1
ENSG00000154978ENST00000428097C9JIM1
ENSG00000154978ENST00000428648C9JIM1
ENSG00000154978ENST00000433959Q96AW1
ENSG00000154978ENST00000452832C9JQ18
ENSG00000154978ENST00000453256C9JIM1
ENSG00000154978ENST00000454227C9J827
ENSG00000154978ENST00000455023C9JTY8
ENSG00000154978ENST00000625836Q96AW1

Expression (GTEx)

0
10
20
30
40
50
60
70
80

References

Pubmed IDYearTitleCitations
175159552007Molecular markers in patients with chronic wounds to guide surgical debridement.76
232430562013MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity.31
195259792009Combined genomic and gene expression microarray profiling identifies ECOP as an upregulated gene in squamous cell carcinomas independent of DNA amplification.11
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
253986642015Epidermal growth factor receptor-coamplified and overexpressed protein (VOPP1) is a putative oncogene in gastric cancer.9
215193302011Loss of VOPP1 overexpression in squamous carcinoma cells induces apoptosis through oxidative cellular injury.8
302857392018VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX.4
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
268604602016Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers.3
289368842017miR-218 suppresses epithelial-to-mesenchymal transition by targeting Robo1 and Ecop in lung adenocarcinoma cells.2

Citation

Dessen P

VOPP1 (VOPP1 WW domain binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51092/vopp1