WASHC2A (WASH complex subunit 2A)

2019-08-01  

Identity

HGNC
WASHC2A
LOCATION
10q11.23
LOCUSID
387680
ALIAS
FAM21A,FAM21B,bA56A21.1,bA98I6.1

Other Information

Locus ID:

NCBI: 387680
HGNC: 23416
Ensembl: ENSG00000099290

Variants:

dbSNP: 387680
ClinVar: 387680
TCGA: ENSG00000099290
COSMIC: WASHC2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099290ENST00000282633Q641Q2
ENSG00000099290ENST00000314664E7ESD2
ENSG00000099290ENST00000351071Q641Q2
ENSG00000099290ENST00000399339F8W7U3
ENSG00000099290ENST00000434114Q5T1D7
ENSG00000099290ENST00000454806B1AP61
ENSG00000099290ENST00000611324A0A087WYF6

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
269566592016FAM21 directs SNX27-retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus.21
297355452018Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.6

Citation

Dessen P

WASHC2A (WASH complex subunit 2A)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58098/washc2a