WASHC2C (WASH complex subunit 2C)

2016-11-01  

Identity

HGNC
WASHC2C
LOCATION
10q11.22
LOCUSID
253725
ALIAS
FAM21A,FAM21C,VPEF

Other Information

Locus ID:

NCBI: 253725
MIM: 613631
HGNC: 23414
Ensembl: ENSG00000172661

Variants:

dbSNP: 253725
ClinVar: 253725
TCGA: ENSG00000172661
COSMIC: WASHC2C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172661ENST00000336378A0A0A0MR88
ENSG00000172661ENST00000359860J3KP36
ENSG00000172661ENST00000374362Q9Y4E1
ENSG00000172661ENST00000420848A0A0A0MT65
ENSG00000172661ENST00000537517Q9Y4E1
ENSG00000172661ENST00000540872Q9Y4E1
ENSG00000172661ENST00000623400A0A096LPC5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
225130872012Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer.71
254311352015Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.10
185506752008A novel cellular protein, VPEF, facilitates vaccinia virus penetration into HeLa cells through fluid phase endocytosis.0
199228742009A FAM21-containing WASH complex regulates retromer-dependent sorting.0

Citation

Dessen P

WASHC2C (WASH complex subunit 2C)

Atlas Genet Cytogenet Oncol Haematol. 2016-11-01

Online version: http://atlasgeneticsoncology.org/gene/78794/washc2c