WDR46 (WD repeat domain 46)

2014-11-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
BING4,C6orf11,FP221,UTP7
FUSION GENES

Other Information

Locus ID:

NCBI: 9277
MIM: 611440
HGNC: 13923
Ensembl: ENSG00000227057

Variants:

dbSNP: 9277
ClinVar: 9277
TCGA: ENSG00000227057
COSMIC: WDR46

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000227057ENST00000374617O15213
ENSG00000227057ENST00000444176H0Y6G3

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
238481942013Nucleolar scaffold protein, WDR46, determines the granular compartmental localization of nucleolin and DDX21.4

Citation

Dessen P

WDR46 (WD repeat domain 46)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75717/wdr46