WDR6 (WD repeat domain 6)

2016-10-01  

Identity

HGNC
WDR6
LOCATION
3p21.31
LOCUSID
11180
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11180
MIM: 606031
HGNC: 12758
Ensembl: ENSG00000178252

Variants:

dbSNP: 11180
ClinVar: 11180
TCGA: ENSG00000178252
COSMIC: WDR6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178252ENST00000395474A0A087X295
ENSG00000178252ENST00000415265E9PBK6
ENSG00000178252ENST00000419837C9JFP6
ENSG00000178252ENST00000420783E5RFX3
ENSG00000178252ENST00000429900V9GZ48
ENSG00000178252ENST00000438660C9K020
ENSG00000178252ENST00000448293E9PDU5
ENSG00000178252ENST00000452875F8WE36
ENSG00000178252ENST00000489427V9GYU1
ENSG00000178252ENST00000491365V9GZ65
ENSG00000178252ENST00000608424Q9NNW5
ENSG00000178252ENST00000610967A0A087X295
ENSG00000178252ENST00000615452Q6PKC6
ENSG00000178252ENST00000627177F8WE36

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
262426272015Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L-C7L- Mutant.26
172161282007Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction.15
177202792009Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity.6

Citation

Dessen P

WDR6 (WD repeat domain 6)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56110/wdr6