WDR74 (WD repeat domain 74)

2014-11-01  

Identity

HGNC
LOCATION
11q12.3
LOCUSID
ALIAS
Nsa1
FUSION GENES

Other Information

Locus ID:

NCBI: 54663
MIM: 617947
HGNC: 25529
Ensembl: ENSG00000133316

Variants:

dbSNP: 54663
ClinVar: 54663
TCGA: ENSG00000133316
COSMIC: WDR74

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133316ENST00000278856Q6RFH5
ENSG00000133316ENST00000311713Q6RFH5
ENSG00000133316ENST00000525239Q6RFH5
ENSG00000133316ENST00000525752E9PS41
ENSG00000133316ENST00000529106Q6RFH5
ENSG00000133316ENST00000536401H0YFP2
ENSG00000133316ENST00000538098F5GYL6
ENSG00000133316ENST00000542347F5H0Q8

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
264566512015AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74.9
291076932018WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2.6
305944652018WDR74 functions as a novel coactivator in TGF-β signaling.0

Citation

Dessen P

WDR74 (WD repeat domain 74)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75729/wdr74