WEE2 (WEE2 oocyte meiosis inhibiting kinase)

2019-08-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
OOMD5,WEE1B

Other Information

Locus ID:

NCBI: 494551
MIM: 614084
HGNC: 19684
Ensembl: ENSG00000214102

Variants:

dbSNP: 494551
ClinVar: 494551
TCGA: ENSG00000214102
COSMIC: WEE2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214102ENST00000397541P0C1S8
ENSG00000214102ENST00000493845H7C5P0

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Cell cycleKEGGko04110
Cell cycleKEGGhsa04110
Cell cycle - G2/M transitionKEGGhsa_M00693
Cell cycle - G2/M transitionKEGGM00693

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
296063002018Homozygous Mutations in WEE2 Cause Fertilization Failure and Female Infertility.0
304718572019Hepatitis B virus X protein related lncRNA WEE2-AS1 promotes hepatocellular carcinoma proliferation and invasion.0
306280602019Novel mutations in WEE2: Expanding the spectrum of mutations responsible for human fertilization failure.0
308275232019New biallelic mutations in WEE2: expanding the spectrum of mutations that cause fertilization failure or poor fertilization.0
308275242019Novel WEE2 gene variants identified in patients with fertilization failure and female infertility.0
314288872019Novel compound heterozygous mutations in WEE2 causes female infertility and fertilization failure.0

Citation

Dessen P

WEE2 (WEE2 oocyte meiosis inhibiting kinase)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58088/wee2