WFDC2 (WAP four-disulfide core domain 2)

2003-06-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
EDDM4,HE4,WAP5,dJ461P17.6
FUSION GENES

Other Information

Locus ID:

NCBI: 10406
MIM: 617548
HGNC: 15939
Ensembl: ENSG00000101443

Variants:

dbSNP: 10406
ClinVar: 10406
TCGA: ENSG00000101443
COSMIC: WFDC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101443ENST00000217425Q14508
ENSG00000101443ENST00000339946Q14508
ENSG00000101443ENST00000342873Q14508
ENSG00000101443ENST00000372676Q14508
ENSG00000101443ENST00000372676A0A384MTN6
ENSG00000101443ENST00000447118A8K2M3

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380488992024Serum human epididymis protein 4 is associated with disease severity in patients with IgA nephropathy.0
381761272024Prognostic value of HE4 in advanced-stage, high-grade serous ovarian cancer: Analysis of HE4 kinetics during NACT, predicting surgical outcome and recurrence in comparison to CA125.1
382857952024Human Epididymis Protein 4 (HE4) and Cancer Antigen 125 (CA125) for Prediction of Optimal Primary Surgery in Non-Mucinous Epithelial Ovarian Cancer.0
385989002024Human epididymis protein 4: Analysis of national health and nutrition examination survey data.0
386263552024Recessively Inherited Deficiency of Secreted WFDC2 (HE4) Causes Nasal Polyposis and Bronchiectasis.2
380488992024Serum human epididymis protein 4 is associated with disease severity in patients with IgA nephropathy.0
381761272024Prognostic value of HE4 in advanced-stage, high-grade serous ovarian cancer: Analysis of HE4 kinetics during NACT, predicting surgical outcome and recurrence in comparison to CA125.1
382857952024Human Epididymis Protein 4 (HE4) and Cancer Antigen 125 (CA125) for Prediction of Optimal Primary Surgery in Non-Mucinous Epithelial Ovarian Cancer.0
385989002024Human epididymis protein 4: Analysis of national health and nutrition examination survey data.0
386263552024Recessively Inherited Deficiency of Secreted WFDC2 (HE4) Causes Nasal Polyposis and Bronchiectasis.2
365257562023Evaluation of HE4 as a prognostic biomarker in uterine cervical cancer().1
365771602023Human epididymis protein 4 as a clinical biomarker in identifying interstitial lung disease in patients with idiopathic inflammatory myopathies.2
365962802023The Utility of Preoperative Serum CA125 Combined with HE4 to Predict Lymph Node Metastasis in Endometrial Cancer.1
367211122023Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma.3
376035032023Diagnostic value of serum human epididymis protein 4, carbohydrate antigen 125 and their combination in endometrial cancer: A meta-analysis.2

Citation

Dessen P

WFDC2 (WAP four-disulfide core domain 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42808/wfdc2