Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81029
MIM: 606361
HGNC: 16265
Ensembl: ENSG00000111186
Variants:
dbSNP: 81029
ClinVar: 81029
TCGA: ENSG00000111186
COSMIC: WNT5B
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | 23817222 | |
| PA164713176 | Platinum compounds | Chemical | ClinicalAnnotation | associated | PD | 24980784 | |
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 24980784 | |
| PA443756 | Colonic Neoplasms | Disease | ClinicalAnnotation | associated | PD | 23817222 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37971882 | 2024 | DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells. | 0 |
| 38531660 | 2024 | Role of Wnt5b-Ror1 signaling in the proliferation of pancreatic ductal adenocarcinoma cells. | 0 |
| 38689429 | 2024 | WNT5B drives osteosarcoma stemness, chemoresistance and metastasis. | 2 |
| 37971882 | 2024 | DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells. | 0 |
| 38531660 | 2024 | Role of Wnt5b-Ror1 signaling in the proliferation of pancreatic ductal adenocarcinoma cells. | 0 |
| 38689429 | 2024 | WNT5B drives osteosarcoma stemness, chemoresistance and metastasis. | 2 |
| 34906330 | 2022 | Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts. | 8 |
| 34906330 | 2022 | Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts. | 8 |
| 34536574 | 2021 | Exosome-mediated circ_0001846 participates in IL-1β-induced chondrocyte cell damage by miR-149-5p-dependent regulation of WNT5B. | 14 |
| 34536574 | 2021 | Exosome-mediated circ_0001846 participates in IL-1β-induced chondrocyte cell damage by miR-149-5p-dependent regulation of WNT5B. | 14 |
| 31666682 | 2020 | WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression. | 18 |
| 32092330 | 2020 | Up-regulated miR-374a-3p relieves lipopolysaccharides induced injury in CHON-001 cells via regulating Wingless-type MMTV integration site family member 5B. | 8 |
| 32561739 | 2020 | The lncRNA RP11-142A22.4 promotes adipogenesis by sponging miR-587 to modulate Wnt5β expression. | 16 |
| 31666682 | 2020 | WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression. | 18 |
| 32092330 | 2020 | Up-regulated miR-374a-3p relieves lipopolysaccharides induced injury in CHON-001 cells via regulating Wingless-type MMTV integration site family member 5B. | 8 |
Citation
Dessen P
WNT5B (Wnt family member 5B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42826/wnt5b
