WNT9B (Wnt family member 9B)

2003-06-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
WNT14B,WNT15
FUSION GENES

Other Information

Locus ID:

NCBI: 7484
MIM: 602864
HGNC: 12779
Ensembl: ENSG00000158955

Variants:

dbSNP: 7484
ClinVar: 7484
TCGA: ENSG00000158955
COSMIC: WNT9B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158955ENST00000290015O14905
ENSG00000158955ENST00000393461E7EPC3
ENSG00000158955ENST00000575372I3L0L8

Expression (GTEx)

0
1
2
3

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Wnt signaling pathwayKEGGko04310
MelanogenesisKEGGko04916
Basal cell carcinomaKEGGko05217
mTOR signaling pathwayKEGGhsa04150
Wnt signaling pathwayKEGGhsa04310
MelanogenesisKEGGhsa04916
Pathways in cancerKEGGhsa05200
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Wnt signalingKEGGhsa_M00677
Wnt signalingKEGGM00677
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
239740412013Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.82
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
184133252008Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate.58
208909342010Studies with Wnt genes and nonsyndromic cleft lip and palate.30
237852852013Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses.29
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
206723502010Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate.13
248523672014Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder.7
191713302009Mutational analysis of the WNT gene family in women with Mayer-Rokitansky-Kuster-Hauser syndrome.6
244375842015Association of WNT9B Gene Polymorphisms With Nonsyndromic Cleft Lip With or Without Cleft Palate in Brazilian Nuclear Families.5

Citation

Dessen P

WNT9B (Wnt family member 9B)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42833/wnt9b