XIST (X inactive specific transcript)

2007-02-01  

Identity

HGNC
LOCATION
Xq13.2
LOCUSID
ALIAS
DXS1089,DXS399E,LINC00001,NCRNA00001,SXI1,swd66
FUSION GENES

Other Information

Locus ID:

NCBI: 7503
MIM: 314670
HGNC: 12810
Ensembl: ENSG00000229807

Variants:

dbSNP: 7503
ClinVar: 7503
TCGA: ENSG00000229807
COSMIC: XIST

RNA/Proteins

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
258436282015Systematic discovery of Xist RNA binding proteins.268
276025182016m(6)A RNA methylation promotes XIST-mediated transcriptional repression.207
255787802015Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152.114
2005228220102-D structure of the A region of Xist RNA and its implication for PRC2 association.95
276200042016Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression.78
90692841997Xist has properties of the X-chromosome inactivation centre.72
275017562016Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression.64
271008972016MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST.57
120725692002An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells.56
212129492011Expression and function of a large non-coding RNA gene XIST in human cancer.55

Citation

Dessen P

XIST (X inactive specific transcript)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45591/xist