XPO4 (exportin 4)

2011-06-01 Affiliation

Identity

HGNC

XPO4

LOCATION

13q12.11

LOCUSID

64328

ALIAS

exp4

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 64328
MIM: 611449
HGNC: 17796
Ensembl: ENSG00000132953

Variants:

dbSNP: 64328
ClinVar: 64328
TCGA: ENSG00000132953
COSMIC: XPO4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000132953	ENST00000255305	Q9C0E2
ENSG00000132953	ENST00000400602	F2Z2X4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	75
16449645	2006	The mechanism of nuclear export of Smad3 involves exportin 4 and Ran.	40
21332550	2011	Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma.	10
27306458	2016	Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.	10
21991335	2011	Exportin 4 interacts with Sox9 through the HMG Box and inhibits the DNA binding of Sox9.	6
25911113	2015	Multiple exportins influence thyroid hormone receptor localization.	6
24597692	2014	Exportin 4 gene expression and DNA promoter methylation status in chronic hepatitis B virus infection.	3
26293807	2015	Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease.	1

Citation

Dessen P

XPO4 (exportin 4)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52233/xpo4