XPO6 (exportin 6)

2016-10-01  

Identity

HGNC
LOCATION
16p12.1
LOCUSID
ALIAS
EXP6,RANBP20
FUSION GENES

Other Information

Locus ID:

NCBI: 23214
MIM: 608411
HGNC: 19733
Ensembl: ENSG00000169180

Variants:

dbSNP: 23214
ClinVar: 23214
TCGA: ENSG00000169180
COSMIC: XPO6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169180ENST00000304658Q96QU8
ENSG00000169180ENST00000564905H3BPG8
ENSG00000169180ENST00000565698Q96QU8
ENSG00000169180ENST00000566073H3BRJ6
ENSG00000169180ENST00000566175I3L2D7
ENSG00000169180ENST00000568065H3BRV5
ENSG00000169180ENST00000569315H3BMW9
ENSG00000169180ENST00000569951H3BUP8
ENSG00000169180ENST00000570033H3BR41
ENSG00000169180ENST00000573275I3L0S8
ENSG00000169180ENST00000574435I3L2K0

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
145929892003Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.100
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
285915812017Laminin-111 and the Level of Nuclear Actin Regulate Epithelial Quiescence via Exportin-6.18
267098952016Elevated XPO6 expression as a potential prognostic biomarker for prostate cancer recurrence.5
211957112011Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells.3

Citation

Dessen P

XPO6 (exportin 6)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56619/xpo6