XPO7 (exportin 7)

2016-01-01  

Identity

HGNC
XPO7
LOCATION
8p21.3
LOCUSID
23039
ALIAS
EXP7,RANBP16
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23039
MIM: 606140
HGNC: 14108
Ensembl: ENSG00000130227

Variants:

dbSNP: 23039
ClinVar: 23039
TCGA: ENSG00000130227
COSMIC: XPO7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130227ENST00000252512Q9UIA9
ENSG00000130227ENST00000433566E7ESC6
ENSG00000130227ENST00000517551E5RIW1
ENSG00000130227ENST00000521303H0YBE1

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
182562922008STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7.48
152825462004Exportin 7 defines a novel general nuclear export pathway.34
239060232013KPNB1, XPO7 and IPO8 mediate the translocation ofNF-κB/p65 into the nucleus.26
246254502014RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancer.17
297483362018Xpo7 is a broad-spectrum exportin and a nuclear import receptor.12
259111132015Multiple exportins influence thyroid hormone receptor localization.6
205031942010Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.5
256943522015Tumor-specific mutations in low-frequency genes affect their functional properties.4

Citation

Dessen P

XPO7 (exportin 7)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55600/xpo7